Post-translational modifications (PTMs) on tau have long been recognized as affecting
protein function and contributing to neurodegeneration. The explosion of information on …

Vitamins B9 (folate) and B12 are essential water-soluble vitamins that play a crucial role in
the maintenance of one-carbon metabolism: a set of interconnected biochemical pathways …

Homocysteine (Hcy) is a sulfur-containing non-proteinogenic amino acid formed during the
metabolism of the essential amino acid methionine. Hcy is considered a risk factor for …

Post-translational modifications (PTM) decorate proteins to provide functional heterogeneity
to an existing proteome. The large number of known PTMs highlights the many ways that …

Significance: A growing body of clinical and experimental evidence has challenged the
traditional understanding that only the adaptive immune system can mount immunological …

Preventive healthcare asks for the development of cheap, precise and non-invasive sensor
devices for the early detection of diseases and continuous population screening. The actual …

Immune checkpoint inhibitors targeting programmed cell death protein 1 (PD-1) or
programmed cell death 1 ligand 1 (PD-L1) have enabled some patients with cancer to …

While the oxygen-dependent reversal of lysine N ɛ-methylation is well established, the
existence of bona fide N ω-methylarginine demethylases (RDMs) is controversial. Lysine …

Post-translational modifications (PTMs) occurring at protein lysine residues, or protein lysine
modifications (PLMs), play critical roles in regulating biological processes. Due to the …

Methylation at DNA, RNA and protein levels plays critical roles in many cellular processes
and is associated with diverse differentiation events, physiological activities and human …