Reprogramming glucose metabolism in cancer: can it be exploited for cancer therapy?
N Hay - Nature Reviews Cancer, 2016 - nature.com
In recent years there has been a growing interest among cancer biologists in cancer
metabolism. This Review summarizes past and recent advances in our understanding of the …
metabolism. This Review summarizes past and recent advances in our understanding of the …
PI3K/AKT/mTOR dysregulation and reprogramming metabolic pathways in renal cancer: Crosstalk with the VHL/HIF axis
Renal cell carcinoma (RCC) represents 85–95% of kidney cancers and is the most frequent
type of renal cancer in adult patients. It accounts for 3% of all cancer cases and is in 7th …
type of renal cancer in adult patients. It accounts for 3% of all cancer cases and is in 7th …
SP1-induced lncRNA-ZFAS1 contributes to colorectal cancer progression via the miR-150-5p/VEGFA axis
X Chen, K Zeng, M Xu, X Hu, X Liu, T Xu, B He… - Cell death & …, 2018 - nature.com
Increasing long non-coding RNAs (lncRNAs) have been reported to play key roles in the
development and progression of various malignancies. ZNFX1 antisense RNA1 (ZFAS1) …
development and progression of various malignancies. ZNFX1 antisense RNA1 (ZFAS1) …
The cross‐talk between Abl2 tyrosine kinase and TGFβ1 signalling modulates the invasion of clear cell renal cell carcinoma cells
S De Marco, B Torsello, E Minutiello, I Morabito… - FEBS …, 2023 - Wiley Online Library
Clear cell Renal Cell Carcinoma (ccRCC) is the most common and metastatic urological
cancer. Molecular players of ccRCC progression and metastasis are not completely known …
cancer. Molecular players of ccRCC progression and metastasis are not completely known …
Inactivation of the AMPK–GATA3–ECHS1 pathway induces fatty acid synthesis that promotes clear cell renal cell carcinoma growth
YY Qu, R Zhao, HL Zhang, Q Zhou, FJ Xu, X Zhang… - Cancer research, 2020 - AACR
The tumorigenic role and underlying mechanisms of lipid accumulation, commonly observed
in many cancers, remain insufficiently understood. In this study, we identified an AMP …
in many cancers, remain insufficiently understood. In this study, we identified an AMP …
MTHFD2 links RNA methylation to metabolic reprogramming in renal cell carcinoma
NH Green, DL Galvan, SS Badal, BH Chang… - Oncogene, 2019 - nature.com
One-carbon metabolism plays a central role in a broad array of metabolic processes
required for the survival and growth of tumor cells. However, the molecular basis of how one …
required for the survival and growth of tumor cells. However, the molecular basis of how one …
[HTML][HTML] miR-150-5p suppresses tumor progression by targeting VEGFA in colorectal cancer
X Chen, X Xu, B Pan, K Zeng, M Xu, X Liu, B He… - Aging (albany …, 2018 - ncbi.nlm.nih.gov
Abstract MicroRNA-150-5p (miR-150-5p) has been implicated in tumor initiation and
progression in a variety of cancers. However, its roles in colorectal cancer (CRC) remain …
progression in a variety of cancers. However, its roles in colorectal cancer (CRC) remain …
Metabolic reprogramming of clear cell renal cell carcinoma
H Zhu, X Wang, S Lu, K Ou - Frontiers in endocrinology, 2023 - frontiersin.org
Clear cell renal cell carcinoma (ccRCC) is a malignancy that exhibits metabolic
reprogramming as a result of genetic mutations. This reprogramming accommodates the …
reprogramming as a result of genetic mutations. This reprogramming accommodates the …
Targeting the transcription factor receptor LXR to treat clear cell renal cell carcinoma: agonist or inverse agonist?
G Wu, Q Wang, Y Xu, J Li, H Zhang, G Qi, Q Xia - Cell death & disease, 2019 - nature.com
Growing evidence indicates that clear cell renal cell carcinoma (ccRCC) is a metabolism-
related disease. Changes in fatty acid (FA) and cholesterol metabolism play important roles …
related disease. Changes in fatty acid (FA) and cholesterol metabolism play important roles …
[HTML][HTML] Systematic analysis of the expression of the mitochondrial ATP synthase (complex V) subunits in clear cell renal cell carcinoma
M Brüggemann, A Gromes, M Poss, D Schmidt… - Translational …, 2017 - Elsevier
Mitochondrial dysfunction is common in cancer and the mitochondrial electron transport
chain is often affected in carcinogenesis. To date, little is known about the expression of the …
chain is often affected in carcinogenesis. To date, little is known about the expression of the …