Heterocycles are an extraordinarily important class of compounds, making up more than half
of all known organic compounds. Heterocycles are present in a wide variety of drugs, most …

More than a decade ago, the question was raised by Sweeney if aziridines are epoxides'
ugly cousins? 1 The overview on the biological properties, synthetic accessibility, and useful …

Synthesis of unsymmetrically substituted pyrazines has been a challenge. The reactivity of α-
imino carbenoids derived from α-diazo oxime ethers has been exploited for pyrazine …

An organocatalytic asymmetric synthesis of δ‐amino‐β‐ketoester derivatives has been
developed. A chiral disulfonimide (DSI) serves as a highly efficient precatalyst for a …

In this study, we developed a highly sensitive assay for xanthine oxidoreductase (XOR)
activity utilizing a combination of [13C2, 15N2] xanthine and liquid chromatography …

This Feature Article introduces the preparation and synthetic utility of α-diazo oxime ethers. α-
Oximino carbenes are useful synthons for N-heterocycles, and can be easily prepared from …

The laxaphyci's B family constitutes a group of five related cyclic lipopeptides isolated from
diverse cyanobacteria from all around the world. This group shares a typical structure of 12 …

Pyrazino compounds such as quinoxalines are 1, 4-diazines with widespread occurrence in
nature. Quinolin-8-amines are isomerically related and valuable scaffolds in organic …

Enantiomerically pure α-amino acids (α-AAs) are, for a long time, considered as a major
class of chiral pools. Their employment in the enantioselective synthesis of natural products …

The first total synthesis of laxaphycin B was accomplished through stepwise automated
Solid Phase Peptide Synthesis (SPPS), leading to the structural revision of its …