Taste buds: cells, signals and synapses

SD Roper, N Chaudhari - Nature Reviews Neuroscience, 2017 - nature.com
The past decade has witnessed a consolidation and refinement of the extraordinary
progress made in taste research. This Review describes recent advances in our …

Salivary amylase: digestion and metabolic syndrome

C Peyrot des Gachons, PAS Breslin - Current diabetes reports, 2016 - Springer
Salivary amylase is a glucose-polymer cleavage enzyme that is produced by the salivary
glands. It comprises a small portion of the total amylase excreted, which is mostly made by …

The macronutrients, appetite, and energy intake

AL Carreiro, J Dhillon, S Gordon… - Annual review of …, 2016 - annualreviews.org
Each of the macronutrients—carbohydrate, protein, and fat—has a unique set of properties
that influences health, but all are a source of energy. The optimal balance of their …

Molecular mechanism of sweetness sensation

GE DuBois - Physiology & behavior, 2016 - Elsevier
The current understanding of peripheral molecular events involved in sweet taste sensation
in humans is reviewed. Included are discussions of the sweetener receptor T1R2/T1R3, its …

Neuroendocrine and metabolic effects of low-calorie and non-calorie sweeteners

E Moriconi, A Feraco, V Marzolla, M Infante… - Frontiers in …, 2020 - frontiersin.org
Since excessive sugar consumption has been related to the development of chronic
metabolic diseases prevalent in the western world, the use of sweeteners has gradually …

Humans can taste glucose oligomers independent of the hT1R2/hT1R3 sweet taste receptor

TJ Lapis, MH Penner, J Lim - Chemical senses, 2016 - academic.oup.com
It is widely accepted that humans can taste mono-and disaccharides as sweet substances,
but they cannot taste longer chain oligo-and polysaccharides. From the evolutionary …

Taste cell-expressed α-glucosidase enzymes contribute to gustatory responses to disaccharides

SK Sukumaran, KK Yee, S Iwata… - Proceedings of the …, 2016 - National Acad Sciences
The primary sweet sensor in mammalian taste cells for sugars and noncaloric sweeteners is
the heteromeric combination of type 1 taste receptors 2 and 3 (T1R2+ T1R3, encoded by …

The functional and neurobiological properties of bad taste

LA Schier, AC Spector - Physiological reviews, 2019 - journals.physiology.org
The gustatory system serves as a critical line of defense against ingesting harmful
substances. Technological advances have fostered the characterization of peripheral …

The neuroscience of sugars in taste, gut-reward, feeding circuits, and obesity

R Gutierrez, E Fonseca, SA Simon - Cellular and Molecular Life Sciences, 2020 - Springer
Throughout the animal kingdom sucrose is one of the most palatable and preferred tastants.
From an evolutionary perspective, this is not surprising as it is a primary source of energy …

Sodium‐glucose cotransporter 1 as a sugar taste sensor in mouse tongue

K Yasumatsu, T Ohkuri, R Yoshida, S Iwata… - Acta …, 2020 - Wiley Online Library
Aim We investigated potential neuron types that code sugar information and how sodium‐
glucose cotransporters (SGLTs) and T1Rs are involved. Methods Whole‐nerve recordings in …