Impaired mitochondrial function often results in excessive production of reactive oxygen
species (ROS) and is involved in the etiology of many chronic diseases, including …

Fatty acids are a major fuel source used to sustain contractile function in heart and oxidative
skeletal muscle. To meet the energy demands of these muscles, the uptake and β-oxidation …

Fatty liver, oxidative stress, and mitochondrial dysfunction are key pathophysiological
features of insulin resistance and obesity. Butyrate, produced by fermentation in the large …

The negative impact of obesity on reproductive success is well documented but the stages at
which development of the conceptus is compromised and the mechanisms responsible for …

A reduced capacity for mitochondrial fatty acid oxidation in skeletal muscle has been
proposed as a major factor leading to the accumulation of intramuscular lipids and their …

Circadian clocks are fundamental physiological regulators of energy homeostasis, but direct
transcriptional targets of the muscle clock machinery are unknown. To understand how the …

A number of studies have reported that a high-fat diet induces increases in mitochondrial
fatty acid oxidation enzymes in muscle. In contrast, in two recent studies raising plasma free …

The aim of this study was to evaluate the distribution of inhibin/activin alpha, beta (A) and
beta (B) subunits and follistatin in immature oocytes and in matured oocytes before and after …

Scope: The hypothalamus is a key brain region involved in the control of feeding and energy
expenditure. Hypothalamic inflammation and oxidative stress are landmarks of both obesity …

Different nutritional components are able, by modulating mitochondrial function and gut
microbiota composition, to influence body composition, metabolic homeostasis and …