Parkinson and depression: review and outlook

G Laux - Journal of neural transmission, 2022 - Springer
Abstract Depression in Parkinson's Disorder (DPD) has been estimated to appear in up to
40% of people with PD and negatively impacts quality of life, motor and cognitive deficits …

Inflammatory markers and depression in Parkinson's disease: a systematic review

LG Ramanzini, LFM Camargo, JOF Silveira… - Neurological …, 2022 - Springer
Background Parkinson's disease (PD) patients experience non-motor symptoms (NMS),
which may appear before motor manifestations. The most common NMS is depression …

Psychometrics and diagnostics of the Italian version of the Beck Depression Inventory-II (BDI-II) in Parkinson's disease

G Maggi, A D'Iorio, EN Aiello, B Poletti, N Ticozzi… - Neurological …, 2023 - Springer
Introduction Depression is one of the most disabling neuropsychiatric manifestations of
Parkinson's disease (PD) and requires proper screening and diagnosis because it affects …

Efficacy of non-pharmacological interventions for depression in individuals with Parkinson's disease: A systematic review and network meta-analysis

Y Wang, X Sun, F Li, Q Li, Y Jin - Frontiers in Aging Neuroscience, 2022 - frontiersin.org
Background Depression in Parkinson's disease (PD) is a major health concern worldwide.
Recently, an increasing number of non-pharmacological interventions have been used in …

Botulinum neurotoxin A ameliorates depressive-like behavior in a reserpine-induced Parkinson's disease mouse model via suppressing hippocampal microglial …

Y Li, Q Yin, Q Li, A Huo, T Shen, J Cao, C Liu… - Acta Pharmacologica …, 2023 - nature.com
Depression is one of the common non-motor symptoms of Parkinson's disease (PD). In the
clinic, botulinum neurotoxin A (BoNT/A) has been used to treat depression. In this study, we …

Prevalence and risk factors for malnutrition in patients with Parkinson's disease

T Yang, Z Zhan, L Zhang, J Zhu, Y Liu, L Zhang… - Frontiers in …, 2020 - frontiersin.org
Objectives: This study aimed to investigate the relationship between nutritional status and
Parkinson's disease (PD) features. Methods: The cohort was composed of 556 Parkinson's …

miR-218-5p and miR-320a-5p as biomarkers for brain disorders: focus on the major depressive disorder and Parkinson's disease

Z Wan, M Rasheed, Y Li, Q Li, P Wang, J Li… - Molecular …, 2023 - Springer
Depression is one of the early and most persistent non-motor symptoms of Parkinson's
disease (PD), which remains ignored, resulting in the underdiagnosis of PD. Unfortunately …

RNA methylations in depression, from pathological mechanism to therapeutic potential

C Li, P Xu, Y Huang, Y Wang, Y Wu, H Li… - Biochemical …, 2023 - Elsevier
Depression is caused by a variety of factors such as genetic factors, biological factors, and
psychosocial factors, and the pathogenesis is complex. RNA methylations and related …

Hydrogen sulfide attenuates depression-like behaviours in Parkinson's disease model rats by improving synaptic plasticity in a hippocampal warburg effect-dependent …

F Liu, Q Tian, HL Tang, X Cheng, W Zou… - Pharmacology …, 2024 - Elsevier
Background Depression is a highly prevalent comorbidity arising in patients with Parkinson's
disease (PD). However, depression in patients with PD is poorly treated. Hydrogen sulfide …

Damaged insula network contributes to depression in Parkinson's disease

P Huang, X Guan, T Guo, Q Zeng, M Xuan, Q Gu… - Frontiers in …, 2020 - frontiersin.org
Background Depression is common in patients with Parkinson's disease (PD). Our previous
studies suggest that depressed PD patients have altered insula structures. It is, however, still …