Thirty years of resistance: Zig-zag through the plant immune system

BPM Ngou, P Ding, JDG Jones - The Plant Cell, 2022 - academic.oup.com
Understanding the plant immune system is crucial for using genetics to protect crops from
diseases. Plants resist pathogens via a two-tiered innate immune detection-and-response …

Plant immune networks

BPM Ngou, JDG Jones, P Ding - Trends in plant science, 2022 - cell.com
Plants have both cell-surface and intracellular receptors to recognize diverse self-and non-
self molecules. Cell-surface pattern recognition receptors (PRRs) recognize extracellular …

The ZAR1 resistosome is a calcium-permeable channel triggering plant immune signaling

G Bi, M Su, N Li, YU Liang, S Dang, J Xu, M Hu… - Cell, 2021 - cell.com
Nucleotide-binding, leucine-rich repeat receptors (NLRs) are major immune receptors in
plants and animals. Upon activation, the Arabidopsis NLR protein ZAR1 forms a pentameric …

A wheat resistosome defines common principles of immune receptor channels

A Förderer, E Li, AW Lawson, Y Deng, Y Sun… - Nature, 2022 - nature.com
Plant intracellular nucleotide-binding leucine-rich repeat receptors (NLRs) detect pathogen
effectors to trigger immune responses. Indirect recognition of a pathogen effector by the …

Plant “helper” immune receptors are Ca2+-permeable nonselective cation channels

P Jacob, NH Kim, F Wu, F El-Kasmi, Y Chi, WG Walton… - Science, 2021 - science.org
Plant nucleotide-binding leucine-rich repeat receptors (NLRs) regulate immunity and cell
death. In Arabidopsis, a subfamily of “helper” NLRs is required by many “sensor” NLRs …

Direct pathogen-induced assembly of an NLR immune receptor complex to form a holoenzyme

S Ma, D Lapin, LI Liu, Y Sun, W Song, X Zhang… - Science, 2020 - science.org
INTRODUCTION Discrimination of self from nonself is pivotal for cellular organisms, as it
allows the perception of pathogenic invaders that might otherwise multiply unchecked and …

Mutual potentiation of plant immunity by cell-surface and intracellular receptors

BPM Ngou, HK Ahn, P Ding, JDG Jones - Nature, 2021 - nature.com
The plant immune system involves cell-surface receptors that detect intercellular pathogen-
derived molecules, and intracellular receptors that activate immunity upon detection of …

Plant immunity: danger perception and signaling

JM Zhou, Y Zhang - Cell, 2020 - cell.com
Plants employ numerous cell-surface and intracellular immune receptors to perceive a
variety of immunogenic signals associated with pathogen infection and subsequently …

Pathogen effector AvrSr35 triggers Sr35 resistosome assembly via a direct recognition mechanism

YB Zhao, MX Liu, TT Chen, X Ma, ZK Li, Z Zheng… - Science …, 2022 - science.org
Nucleotide-binding, leucine-rich repeat receptors (NLRs) perceive pathogen effectors to
trigger plant immunity. The direct recognition mechanism of pathogen effectors by coiled-coil …

Effector‐dependent activation and oligomerization of plant NRC class helper NLRs by sensor NLR immune receptors Rpi‐amr3 and Rpi‐amr1

HK Ahn, X Lin, AC Olave‐Achury, L Derevnina… - The EMBO …, 2023 - embopress.org
Plant pathogens compromise crop yields. Plants have evolved robust innate immunity that
depends in part on intracellular Nucleotide‐binding, Leucine rich‐Repeat (NLR) immune …