Genome-scale functional genomics identify genes preferentially essential for multiple myeloma cells compared to other neoplasias
R de Matos Simoes, R Shirasaki… - Nature cancer, 2023 - nature.com
Clinical progress in multiple myeloma (MM), an incurable plasma cell (PC) neoplasia, has
been driven by therapies that have limited applications beyond MM/PC neoplasias and do …
been driven by therapies that have limited applications beyond MM/PC neoplasias and do …
Natural killer cells affect the natural course, drug resistance, and prognosis of multiple myeloma
L Zhang, X Peng, T Ma, J Liu, Z Yi, J Bai, Y Li… - Frontiers in Cell and …, 2024 - frontiersin.org
Multiple myeloma (MM), a stage-developed plasma cell malignancy, evolves from
monoclonal gammopathy of undetermined significance (MGUS) or smoldering MM (SMM) …
monoclonal gammopathy of undetermined significance (MGUS) or smoldering MM (SMM) …
Deletion of the TMEM30A gene enables leukemic cell evasion of NK cell cytotoxicity
L Kristenson, C Badami, A Ljungberg… - Proceedings of the …, 2024 - National Acad Sciences
Natural killer (NK) cell immunotherapy has gained attention as a promising strategy for
treatment of various malignancies. In this study, we used a genome-wide CRISPR screen to …
treatment of various malignancies. In this study, we used a genome-wide CRISPR screen to …