Autophagy allows for cellular material to be delivered to lysosomes for degradation resulting
in basal or stress-induced turnover of cell components that provide energy and …

Autophagy is an intracellular catabolic self-cannibalism that eliminates dysfunctional
cytoplasmic cargos by the fusion of cargo-containing autophagosomes with lysosomes to …

Normal cells depend on autophagy to maintain cellular homeostasis by recycling damaged
organelles and misfolded proteins and degrading toxic agents. Similar to apoptosis …

Despite the advancement in prognosis, diagnosis and treatment, cancer has emerged as the
second leading cause of disease associated with death in the globe. With the remarkable …

Autophagy is a conserved biological phenomenon that maintains cellular homeostasis
through the clearing of damaged cellular components under cellular stress and offers the …

Simple Summary Tumor dormancy is the period during which patients are asymptomatic
before recurrence and it is difficult to target pharmacologically. Inflammatory cytokines …

Hepatocellular carcinoma (HCC) is among the deadliest malignancies worldwide and still a
pressing clinical problem. Icaritin, a natural compound obtained from the Epimedium genus …

Complex molecular mechanisms define our responses to environmental stimuli. Beyond the
DNA sequence itself, epigenetic machinery orchestrates changes in gene expression …

Lung cancer has a relatively poor prognosis, and the clinical efficacy of targeted drugs
remains unsatisfactory. Therefore, the search for safe and efficient novel antitumor drugs has …

Lysosomal-driven autophagy is a tightly controlled cellular catabolic process that breaks
down and recycles broken or superfluous cell parts. It is involved in several illnesses …