Virus-like particles as a highly efficient vaccine platform: diversity of targets and production systems and advances in clinical development
N Kushnir, SJ Streatfield, V Yusibov - Vaccine, 2012 - Elsevier
Virus-like particles (VLPs) are a class of subunit vaccines that differentiate themselves from
soluble recombinant antigens by stronger protective immunogenicity associated with the …
soluble recombinant antigens by stronger protective immunogenicity associated with the …
Synthetic biology for bioengineering virus‐like particle vaccines
HK Charlton Hume, J Vidigal… - Biotechnology and …, 2019 - Wiley Online Library
Vaccination is the most effective method of disease prevention and control. Many viruses
and bacteria that once caused catastrophic pandemics (eg, smallpox, poliomyelitis …
and bacteria that once caused catastrophic pandemics (eg, smallpox, poliomyelitis …
A comprehensive overview on the production of vaccines in plant-based expression systems and the scope of plant biotechnology to combat against SARS-CoV-2 …
Many pathogenic viral pandemics have caused threats to global health; the COVID-19
pandemic is the latest. Its transmission is growing exponentially all around the globe, putting …
pandemic is the latest. Its transmission is growing exponentially all around the globe, putting …
The use of plants for the production of therapeutic human peptides
C Lico, L Santi, RM Twyman, M Pezzotti, L Avesani - Plant cell reports, 2012 - Springer
Peptides have unique properties that make them useful drug candidates for diverse
indications, including allergy, infectious disease and cancer. Some peptides are intrinsically …
indications, including allergy, infectious disease and cancer. Some peptides are intrinsically …
Plant-based vaccines in combat against coronavirus diseases
B Ortega-Berlanga, T Pniewski - Vaccines, 2022 - mdpi.com
Coronavirus (CoV) diseases, including Middle East Respiratory Syndrome (MERS) and
Severe Acute Respiratory Syndrome (SARS) have gained in importance worldwide …
Severe Acute Respiratory Syndrome (SARS) have gained in importance worldwide …
Virus-like particles displaying envelope domain III of dengue virus type 2 induce virus-specific antibody response in mice
U Arora, P Tyagi, S Swaminathan, N Khanna - Vaccine, 2013 - Elsevier
OBJECTIVE: Currently, dengue represents one of the most significant arboviral disease
worldwide, for which a vaccine is not yet available. Persistent challenges in live viral dengue …
worldwide, for which a vaccine is not yet available. Persistent challenges in live viral dengue …
Plant‐produced candidate countermeasures against emerging and reemerging infections and bioterror agents
SJ Streatfield, N Kushnir… - Plant biotechnology …, 2015 - Wiley Online Library
Despite progress in the prevention and treatment of infectious diseases, they continue to
present a major threat to public health. The frequency of emerging and reemerging …
present a major threat to public health. The frequency of emerging and reemerging …
Two decades of plant-based candidate vaccines: a review of the chimeric protein approaches
RE Soria-Guerra, L Moreno-Fierros… - Plant cell reports, 2011 - Springer
Genetic engineering revolutionized the concept of traditional vaccines since subunit
vaccines became reality. Additionally, over the past two decades plant-derived antigens …
vaccines became reality. Additionally, over the past two decades plant-derived antigens …
Expression of recombinant vaccines and antibodies in plants
K Ko - Monoclonal antibodies in immunodiagnosis and …, 2014 - liebertpub.com
Plants are able to perform post-translational maturations of therapeutic proteins required for
their functional biological activity and suitable in vivo pharmacokinetics. Plants can be a low …
their functional biological activity and suitable in vivo pharmacokinetics. Plants can be a low …
Plant-based vaccines against respiratory diseases: Current status and future prospects
VA Márquez-Escobar, S Rosales-Mendoza… - Expert Review of …, 2017 - Taylor & Francis
Introduction: Respiratory infections have an enormous, worldwide epidemiologic impact on
humans and animals. Among the prophylactic measures, vaccination has the potential to …
humans and animals. Among the prophylactic measures, vaccination has the potential to …