Non-invasive biomarkers for early detection of breast cancer
Simple Summary Early diagnosis of breast cancer greatly increases the chance of cure and
survival from the disease. The mammogram is widely used for early detection of breast …
survival from the disease. The mammogram is widely used for early detection of breast …
Chemometrics in metabolomics—a review in human disease diagnosis
R Madsen, T Lundstedt, J Trygg - Analytica chimica acta, 2010 - Elsevier
Metabolomics is a post genomic research field concerned with developing methods for
analysis of low molecular weight compounds in biological systems, such as cells, organs or …
analysis of low molecular weight compounds in biological systems, such as cells, organs or …
Quantitative analysis of tRNA abundance and modifications by nanopore RNA sequencing
Transfer RNAs (tRNAs) play a central role in protein translation. Studying them has been
difficult in part because a simple method to simultaneously quantify their abundance and …
difficult in part because a simple method to simultaneously quantify their abundance and …
Elemental formula annotation of polar and lipophilic metabolites using 13C, 15N and 34S isotope labelling, in combination with high‐resolution mass spectrometry
P Giavalisco, Y Li, A Matthes, A Eckhardt… - The Plant …, 2011 - Wiley Online Library
The unbiased and comprehensive analysis of metabolites in any organism presents a major
challenge if proper peak annotation and unambiguous assignment of the biological origin of …
challenge if proper peak annotation and unambiguous assignment of the biological origin of …
Cancer metabolomic markers in urine: evidence, techniques and recommendations
SS Dinges, A Hohm, LA Vandergrift, J Nowak… - Nature reviews …, 2019 - nature.com
Urinary tests have been used as noninvasive, cost-effective tools for screening, diagnosis
and monitoring of diseases since ancient times. As we progress through the 21st century …
and monitoring of diseases since ancient times. As we progress through the 21st century …
Early breast cancer detection using untargeted and targeted metabolomics
Breast cancer (BC) is a common cause of morbidity and mortality, particularly in women.
Moreover, the discovery of diagnostic biomarkers for early BC remains a challenging task …
Moreover, the discovery of diagnostic biomarkers for early BC remains a challenging task …
Applications of liquid chromatography coupled to mass spectrometry-based metabolomics in clinical chemistry and toxicology: A review
The metabolome is the set of small molecular mass organic compounds found in a given
biological media. It includes all organic substances naturally occurring from the metabolism …
biological media. It includes all organic substances naturally occurring from the metabolism …
Urine metabolite analysis offers potential early diagnosis of ovarian and breast cancers
CM Slupsky, H Steed, TH Wells, K Dabbs… - Clinical cancer …, 2010 - AACR
Purpose: Metabolomics is a new, rapidly expanding field dedicated to the global study of
metabolites in biological systems. In this article metabolomics is applied to find urinary …
metabolites in biological systems. In this article metabolomics is applied to find urinary …
Metabolomic fingerprinting: challenges and opportunities
AK Kosmides, K Kamisoglu, SE Calvano… - Critical Reviews™ in …, 2013 - dl.begellhouse.com
Systems biology has primarily focused on studying genomics, transcriptomics, and
proteomics and their dynamic interactions. These, however, represent only the potential for a …
proteomics and their dynamic interactions. These, however, represent only the potential for a …
Review of mass spectrometry–based metabolomics in cancer research
DB Liesenfeld, N Habermann, RW Owen… - … , biomarkers & prevention, 2013 - AACR
Metabolomics, the systematic investigation of all metabolites present within a biologic
system, is used in biomarker development for many human diseases, including cancer. In …
system, is used in biomarker development for many human diseases, including cancer. In …