Crohn's disease is an inflammatory bowel disease that is characterized by chronic
inflammation of any part of the gastrointestinal tract, has a progressive and destructive …

Newer Biologic and Small-Molecule Therapies for IBD There is still no cure for inflammatory
bowel disease. This review covers newer treatments that reflect our understanding of the …

Ulcerative colitis [UC] is a chronic inflammatory bowel disease [IBD] characterised by colonic
inflammation extending to a variable extent from the rectum. Care of the patient with UC …

2. Methods Based on the GRADE workflow, the Guidelines Committee of ECCO [GuiCom]
selected a panel of 48 experts supported by a team of methodologists and librarians …

The rapid progress of research into inflammatory bowel disease (IBD) has resulted in
increasingly more treatment options. Different options have different advantages and …

Intestinal immune homeostasis and microbiome structure play a critical role in the
pathogenesis and progress of inflammatory bowel disease (IBD), whereas IBD treatment …

This article is the second in a series of two publications relating to the European Crohn's and
Colitis Organisation [ECCO] evidence-based consensus on the management of Crohn's …

Objective The Epi-IBD cohort is a prospective population-based inception cohort of
unselected patients with inflammatory bowel disease from 29 European centres covering a …

Proposed treatment targets for the management of inflammatory bowel disease (IBD) have
moved beyond symptomatic improvement towards more objective end points, such as …

Tumor necrosis factor-alpha (TNF-α) is a multifunctional Th1 cytokine and one of the most
important inflammatory cytokines. In pregnancy, TNF-α influences hormone synthesis …