Naringenin alleviates paraquat-induced dopaminergic neuronal loss in SH-SY5Y cells and a rat model of Parkinson's disease

MH Ahmad, M Fatima, M Ali, MA Rizvi, AC Mondal - Neuropharmacology, 2021 - Elsevier
Abstract Parkinson's disease (PD), a common neurodegenerative disease is characterized
by the progressive loss of dopaminergic neurons in the substantia nigra. The cause of …

An insight into prodrug strategy for the treatment of Alzheimer's disease

NV Bhilare, VS Marulkar, D Kumar, VK Chatap… - Medicinal Chemistry …, 2022 - Springer
Alzheimer's disease (AD) is the leading cause of dementia worldwide. With 35 million
people over 60 suffering from dementia, new treatments for AD are immediately needed. In …

Piperine-Coated Gold Nanoparticles Alleviate Paraquat-Induced Neurotoxicity in Drosophila melanogaster

S Srivastav, BG Anand, M Fatima… - ACS Chemical …, 2020 - ACS Publications
Parkinson's disease (PD) is the most common progressive neurodegenerative disease
known to impart bradykinesia leading to diverse metabolic complications. Currently, scarcity …

[HTML][HTML] ROS production and mitochondrial dysfunction driven by PU. 1-regulated NOX4-p22phox activation in Aβ-induced retinal pigment epithelial cell injury

J Sun, J Chen, T Li, P Huang, J Li, M Shen, M Gao… - Theranostics, 2020 - ncbi.nlm.nih.gov
Rationale: Amyloid β (Aβ) deposition, an essential pathological process in age-related
macular degeneration (AMD), causes retinal pigment epithelium (RPE) degeneration driven …

Polysaccharide of Taxus chinensis var. mairei Cheng et LKFu attenuates neurotoxicity and cognitive dysfunction in mice with Alzheimer's disease

S Zhang, L Li, J Hu, P Ma, H Zhu - Pharmaceutical Biology, 2020 - Taylor & Francis
Abstract Context Polysaccharide of Taxus chinensis var. mairei Cheng et LK Fu
(Taxaceae)(PTM) functions in anti-apoptosis and antioxidation, but its function on …

Expression of ITPR2 regulated by lncRNA-NONMMUT020270. 2 in LPS-stimulated HT22 cells

L Liu, L Tang, Y Wang, S Liu, Y Zhang - Heliyon, 2024 - cell.com
Background Long non-coding RNA (lncRNA)-NONMMUT020270. 2 is downregulated and
co-expressed with inositol 1, 4, 5-trisphosphate receptor type 2 (ITPR2) in the hippocampus …

An explicitly designed paratope of amyloid-β prevents neuronal apoptosis in vitro and hippocampal damage in rat brain

A Paul, S Kumar, S Kalita, S Kalita, D Sarkar… - Chemical …, 2021 - pubs.rsc.org
Synthetic antibodies hold great promise in combating diseases, diagnosis, and a wide range
of biomedical applications. However, designing a therapeutically amenable, synthetic …

Enhancing amyloid beta inhibition and disintegration by natural compounds: A study utilizing spectroscopy, microscopy and cell biology

R Pariary, G Shome, T Dutta, A Roy, AK Misra… - Biophysical …, 2024 - Elsevier
Amyloid proteins and peptides play a pivotal role in the etiology of various
neurodegenerative diseases, including Alzheimer's disease (AD). Synthetically designed …

A synthetic pro-drug peptide reverses amyloid-β-induced toxicity in the rat model of Alzheimer's disease

S Kumar, S Srivastav, M Fatima, RS Giri… - Journal of …, 2019 - content.iospress.com
Background: Alzheimer's disease (AD), the most prevalent neurodegenerative disorder,
involves the formation of the extracellular amyloid-β (Aβ) plaques and intracellular …

Defining Extracellular Vesicle Mimetic Nanovesicles Protein and RNA Composition, and its Therapeutic Potential

A Nasiri Kenari - 2022 - opal.latrobe.edu.au
Defining Extracellular Vesicle Mimetic- Nanovesicles Protein and RNA Composition, and its
Therapeutic Potential Page 1 Defining Extracellular Vesicle MimeticNanovesicles Protein …