[HTML][HTML] Metabolic dysfunction in polycystic ovary syndrome: Pathogenic role of androgen excess and potential therapeutic strategies

MA Sanchez-Garrido, M Tena-Sempere - Molecular metabolism, 2020 - Elsevier
Background Polycystic ovary syndrome (PCOS) is the most common endocrinopathy among
reproductive age women. Although its cardinal manifestations include hyperandrogenism …

Animal models to understand the etiology and pathophysiology of polycystic ovary syndrome

E Stener-Victorin, V Padmanabhan… - Endocrine …, 2020 - academic.oup.com
More than 1 out of 10 women worldwide are diagnosed with polycystic ovary syndrome
(PCOS), the leading cause of female reproductive and metabolic dysfunction. Despite its …

Characteristics of obesity in polycystic ovary syndrome: Etiology, treatment, and genetics

CJ Glueck, N Goldenberg - Metabolism, 2019 - Elsevier
Polycystic ovary syndrome (PCOS) has multiple etiologies including ovarian and adrenal
hyperandrogenism, neuro-endocrine and hypothalamic-pituitary dysfunction, and disorders …

Scientific statement on the diagnostic criteria, epidemiology, pathophysiology, and molecular genetics of polycystic ovary syndrome

DA Dumesic, SE Oberfield, E Stener-Victorin… - Endocrine …, 2015 - academic.oup.com
Polycystic ovary syndrome (PCOS) is a heterogeneous and complex disorder that has both
adverse reproductive and metabolic implications for affected women. However, there is …

Insulin resistance and the polycystic ovary syndrome revisited: an update on mechanisms and implications

E Diamanti-Kandarakis, A Dunaif - Endocrine reviews, 2012 - academic.oup.com
Polycystic ovary syndrome (PCOS) is now recognized as an important metabolic as well as
reproductive disorder conferring substantially increased risk for type 2 diabetes. Affected …

[HTML][HTML] Consensus on women's health aspects of polycystic ovary syndrome (PCOS): the Amsterdam ESHRE/ASRM-Sponsored 3rd PCOS Consensus Workshop …

BCJM Fauser, BC Tarlatzis, RW Rebar, RS Legro… - Fertility and sterility, 2012 - Elsevier
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in females, with
a high prevalence. The etiology of this heterogeneous condition remains obscure, and its …

Polycystic ovary syndrome and mitochondrial dysfunction

J Zhang, Y Bao, X Zhou, L Zheng - Reproductive Biology and …, 2019 - Springer
Polycystic ovary syndrome (PCOS) is a prevalent hormonal disorder of premenopausal
women worldwide and is characterized by reproductive, endocrine, and metabolic …

Myo-inositol effects in women with PCOS: a meta-analysis of randomized controlled trials

V Unfer, F Facchinetti, B Orrù, B Giordani… - Endocrine …, 2017 - ec.bioscientifica.com
Myo-inositol (MI) supplementation in women with polycystic ovary syndrome (PCOS) has
been evaluated over the last years. Many hormonal and reproductive impairments …

Insulin and hyperandrogenism in women with polycystic ovary syndrome

CG Baptiste, MC Battista, A Trottier… - The Journal of steroid …, 2010 - Elsevier
Polycystic ovary syndrome (PCOS) is a very common endocrine disorder characterized by
chronic anovulation, clinical and/or biochemical hyperandrogenism, and/or polycystic …

The proliferating role of insulin and insulin-like growth factors in cancer

EJ Gallagher, D LeRoith - Trends in Endocrinology & Metabolism, 2010 - cell.com
Epidemiological studies have reported an increased risk of cancer in people with type 2
diabetes (T2DM) and obesity, related in part to hyperinsulinemia, secondary to insulin …