PET imaging of inflammation in atherosclerosis

JM Tarkin, FR Joshi, JHF Rudd - Nature Reviews Cardiology, 2014 - nature.com
PET imaging of atherosclerosis can quantify several in vivo pathological processes
occurring within the arterial system. 18F-fluorodeoxyglucose (FDG) is the most-commonly …

Adipocyte fatty acid binding protein: a novel adipokine involved in the pathogenesis of metabolic and vascular disease?

S Kralisch, M Fasshauer - Diabetologia, 2013 - Springer
Adipocyte fatty acid binding protein (AFABP, also known as aP2 and FABP4) has recently
been introduced as a novel fat-derived circulating protein. AFABP serum concentrations are …

Position paper of the Cardiovascular Committee of the European Association of Nuclear Medicine (EANM) on PET imaging of atherosclerosis

J Bucerius, F Hyafil, HJ Verberne, RHJA Slart… - European journal of …, 2016 - Springer
Cardiovascular diseases are the leading cause of death not only in Europe but also in the
rest of the World. Preventive measures, however, often fail and cardiovascular disease may …

Effect of intensive versus moderate lipid-lowering therapy on epicardial adipose tissue in hyperlipidemic post-menopausal women: a substudy of the BELLES trial …

N Alexopoulos, BH Melek, CD Arepalli… - Journal of the American …, 2013 - jacc.org
Objectives: This study sought to evaluate the effect of intensive and moderate statin therapy
on epicardial adipose tissue (EAT). Background: EAT has been associated with coronary …

Noninvasive plaque imaging to accelerate coronary artery disease drug development

GA Figtree, PD Adamson, C Antoniades… - Circulation, 2022 - Am Heart Assoc
Coronary artery disease (CAD) remains the leading cause of adult mortality globally.
Targeting known modifiable risk factors has had substantial benefit, but there remains a …

[HTML][HTML] TNF-α antagonist and vascular inflammation in patients with psoriasis vulgaris: a randomized placebo-controlled study

R Bissonnette, F Harel, JG Krueger, MC Guertin… - Journal of Investigative …, 2017 - Elsevier
Vascular inflammation is increased in patients with psoriasis. This randomized, double-
blind, multicenter study evaluated the effects of tumor necrosis factor-α antagonist …

Thresholds for Arterial Wall Inflammation Quantified by 18F-FDG PET Imaging: Implications for Vascular Interventional Studies

FM van der Valk, SL Verweij, KAH Zwinderman… - JACC: Cardiovascular …, 2016 - jacc.org
Objectives: This study assessed 5 frequently applied arterial 18fluorodeoxyglucose (18F-
FDG) uptake metrics in healthy control subjects, those with risk factors and patients with …

Effect of statin therapy on arterial wall inflammation based on 18F-FDG PET/CT: a systematic review and meta-analysis of interventional studies

M Pirro, LE Simental-Mendía, V Bianconi… - Journal of clinical …, 2019 - mdpi.com
Aim. To evaluate by meta-analysis of interventional studies the effect of statin therapy on
arterial wall inflammation. Background. Arterial exposure to low-density lipoprotein (LDL) …

PET imaging of atherosclerotic disease: advancing plaque assessment from anatomy to pathophysiology

NR Evans, JM Tarkin, MM Chowdhury… - Current atherosclerosis …, 2016 - Springer
Atherosclerosis is a leading cause of morbidity and mortality. It is now widely recognized that
the disease is more than simply a flow-limiting process and that the atheromatous plaque …

[HTML][HTML] Semaglutide reduces vascular inflammation investigated by PET in a rabbit model of advanced atherosclerosis

JK Jensen, T Binderup, CE Grandjean, S Bentsen… - Atherosclerosis, 2022 - Elsevier
Background and aims The objective of this study was to investigate the effects of
semaglutide, a long acting glucagon-like peptide-1 receptor agonist, on atherosclerotic …