The spectrum of achalasia: lessons from studies of pathophysiology and high-resolution manometry

PJ Kahrilas, G Boeckxstaens - Gastroenterology, 2013 - Elsevier
High-resolution manometry and recently described analysis algorithms, summarized in the
Chicago Classification, have increased the recognition of achalasia. It has become apparent …

Advances in management of esophageal motility disorders

PJ Kahrilas, AJ Bredenoord, DA Carlson… - Clinical …, 2018 - Elsevier
The widespread adoption of high-resolution manometry (HRM) has led to a restructuring in
the classification of esophageal motility disorder classification summarized in the Chicago …

ACG clinical guidelines: clinical use of esophageal physiologic testing

CP Gyawali, DA Carlson, JW Chen… - Official journal of the …, 2020 - journals.lww.com
Esophageal symptoms are common and may indicate the presence of gastroesophageal
reflux disease (GERD), structural processes, motor dysfunction, behavioral conditions, or …

ACG clinical guidelines: diagnosis and management of achalasia

MF Vaezi, JE Pandolfino, RH Yadlapati… - Official journal of the …, 2020 - journals.lww.com
Achalasia is an esophageal motility disorder characterized by aberrant peristalsis and
insufficient relaxation of the lower esophageal sphincter. Patients most commonly present …

Timed barium swallow: diagnostic role and predictive value in untreated achalasia, esophagogastric junction outflow obstruction, and non-achalasia dysphagia

W Blonski, A Kumar, J Feldman… - Official journal of the …, 2018 - journals.lww.com
OBJECTIVES: Timed barium swallow (TBS) assesses esophageal emptying in patients with
achalasia and is considered the standard workup for patients with dysphagia. Our aim was …

Distensibility of the esophagogastric junction assessed with the functional lumen imaging probe (FLIP™) in achalasia patients

JE Pandolfino, A de Ruigh, F Nicodème… - …, 2013 - Wiley Online Library
Background The functional lumen imaging probe (FLIP), measures esophagogastric
junction (EGJ) distensibility (cross‐sectional area/luminal pressure) during volume …

The functional lumen imaging probe detects esophageal contractility not observed with manometry in patients with achalasia

DA Carlson, Z Lin, PJ Kahrilas, J Sternbach… - Gastroenterology, 2015 - Elsevier
Background & Aims The functional lumen imaging probe (FLIP) could improve the
characterization of achalasia subtypes by detecting nonocclusive esophageal contractions …

Intraoperative measurement of esophagogastric junction cross-sectional area by impedance planimetry correlates with clinical outcomes of peroral endoscopic …

S Ngamruengphong, BHA von Rahden, J Filser… - Surgical …, 2016 - Springer
Background Peroral endoscopic myotomy (POEM) has been introduced as an endoscopic
alternative to surgical myotomy. The endoluminal functional lumen imaging probe …

Peroral endoscopic myotomy: an evolving treatment for achalasia

R Bechara, H Ikeda, H Inoue - Nature Reviews Gastroenterology & …, 2015 - nature.com
Peroral endoscopic myotomy (POEM) was first performed in Japan in 2008 for
uncomplicated achalasia. With excellent results, it was adopted by highly skilled …

Presentation, diagnosis, and management of achalasia

JE Pandolfino, PJ Kahrilas - Clinical Gastroenterology and …, 2013 - cghjournal.org
The literal definition of achalasia is “failure of a ring muscle to relax.” Despite this general
definition, the term has been adopted to specifically describe esophageal achalasia, an …