[HTML][HTML] Time domains of the hypoxic ventilatory response and their molecular basis
ME Pamenter, FL Powell - Comprehensive Physiology, 2016 - ncbi.nlm.nih.gov
Ventilatory responses to hypoxia vary widely depending on the pattern and length of hypoxic
exposure. Acute, prolonged, or intermittent hypoxic episodes can increase or decrease …
exposure. Acute, prolonged, or intermittent hypoxic episodes can increase or decrease …
[HTML][HTML] Astrocytes in the nucleus of the solitary tract: Contributions to neural circuits controlling physiology
AJ MacDonald, KLJ Ellacott - Physiology & behavior, 2020 - Elsevier
The nucleus of the solitary tract (NTS) is the primary brainstem centre for the integration of
physiological information from the periphery transmitted via the vagus nerve. In turn, the NTS …
physiological information from the periphery transmitted via the vagus nerve. In turn, the NTS …
Minocycline blocks glial cell activation and ventilatory acclimatization to hypoxia
Ventilatory acclimatization to hypoxia (VAH) is the time-dependent increase in ventilation,
which persists upon return to normoxia and involves plasticity in both central nervous system …
which persists upon return to normoxia and involves plasticity in both central nervous system …
Neuroinflammation in the NTS is associated with changes in cardiovascular reflexes during systemic inflammation
MR Amorim, JL de Deus, RA Cazuza… - Journal of …, 2019 - Springer
Background Lipopolysaccharide (LPS)-induced systemic inflammation (SI) is associated
with neuroinflammation in the brain, hypotension, tachycardia, and multiple organs …
with neuroinflammation in the brain, hypotension, tachycardia, and multiple organs …
Loss of Atoh1 from neurons regulating hypoxic and hypercapnic chemoresponses causes neonatal respiratory failure in mice
ME van der Heijden, HY Zoghbi - Elife, 2018 - elifesciences.org
Atoh1-null mice die at birth from respiratory failure, but the precise cause has remained
elusive. Loss of Atoh1 from various components of the respiratory circuitry (eg the …
elusive. Loss of Atoh1 from various components of the respiratory circuitry (eg the …
Astrocytes modulate cerebral blood flow and neuronal response to cocaine in prefrontal cortex
Cocaine affects both cerebral blood vessels and neuronal activity in brain. Cocaine can also
disrupt astrocytes, which modulate neurovascular coupling—a process that regulates …
disrupt astrocytes, which modulate neurovascular coupling—a process that regulates …
Chemogenetic inhibition of NTS astrocytes normalizes cardiac autonomic control and ameliorate hypertension during chronic intermittent hypoxia
K Pereyra, A Las Heras, C Toledo, E Díaz-Jara… - Biological Research, 2023 - Springer
Background Obstructive sleep apnea (OSA) is characterized by recurrent episodes of
chronic intermittent hypoxia (CIH), which has been linked to the development of …
chronic intermittent hypoxia (CIH), which has been linked to the development of …
Peripheral-to-central immune communication at the area postrema glial-barrier following bleomycin-induced sterile lung injury in adult rats
DG Litvin, SJ Denstaedt, LF Borkowski… - Brain, behavior, and …, 2020 - Elsevier
The pathways for peripheral-to-central immune communication (P→ C I-comm) following
sterile lung injury (SLI) are unknown. SLI evokes systemic and central inflammation, which …
sterile lung injury (SLI) are unknown. SLI evokes systemic and central inflammation, which …
The role of astrocytes in the nucleus tractus solitarii in maintaining central control of autonomic function
D Martinez, DD Kline - American Journal of Physiology …, 2021 - journals.physiology.org
The nucleus tractus solitarii (nTS) is the first central site for the termination and integration of
autonomic and respiratory sensory information. Sensory afferents terminating in the nTS as …
autonomic and respiratory sensory information. Sensory afferents terminating in the nTS as …
Enhancement of excitatory transmission in NTS neurons projecting to ventral medulla of rats exposed to sustained hypoxia is blunted by minocycline
L Lima‐Silveira, D Accorsi‐Mendonça… - The Journal of …, 2019 - Wiley Online Library
Key points Rats subjected to sustained hypoxia (SH) present increases in arterial pressure
(AP) and in glutamatergic transmission in the nucleus tractus solitarius (NTS) neurons …
(AP) and in glutamatergic transmission in the nucleus tractus solitarius (NTS) neurons …