[HTML][HTML] Therapeutic applications of curcumin nanoformulations

MM Yallapu, PKB Nagesh, M Jaggi, SC Chauhan - The AAPS journal, 2015 - Springer
Curcumin (diferuloylmethane) is a bioactive and major phenolic component of turmeric
derived from the rhizomes of curcuma longa linn. For centuries, curcumin has exhibited …

[HTML][HTML] The Nrf2 pathway in ischemic stroke: a review

M Farina, LE Vieira, B Buttari, E Profumo, L Saso - Molecules, 2021 - mdpi.com
Ischemic stroke, characterized by the sudden loss of blood flow in specific area (s) of the
brain, is the leading cause of permanent disability and is among the leading causes of death …

Poly (vinyl alcohol)-gelatin-sericin copolymerized film fortified with vesicle-entrapped demethoxycurcumin/bisdemethoxycurcumin for improved stability, antibacterial …

S Singh, N Supaweera, OF Nwabor… - International Journal of …, 2024 - Elsevier
Vesicle delivery carriers, used to stabilize hydrophobic drugs, are characterized by the
propensity to aggregate, and fuse, limiting its applications. Fortifying vesicle-entrapped …

Curcumin attenuates glutamate neurotoxicity in the hippocampus by suppression of ER stress-associated TXNIP/NLRP3 inflammasome activation in a manner …

Y Li, J Li, S Li, Y Li, X Wang, B Liu, Q Fu… - Toxicology and Applied …, 2015 - Elsevier
Curcumin is a natural polyphenolic compound in Curcuma longa with beneficial effects on
neuronal protection. This study aims to investigate the action of curcumin in the …

[HTML][HTML] Dodging blood brain barrier with “nano” warriors: Novel strategy against ischemic stroke

S Parvez, M Kaushik, M Ali, MM Alam, J Ali… - Theranostics, 2022 - ncbi.nlm.nih.gov
Ischemic stroke (IS) is one of the leading causes of death and disability resulting in
inevitable burden globally. Ischemic injury initiates cascade of pathological events …

Curcumin by down-regulating NF-kB and elevating Nrf2, reduces brain edema and neurological dysfunction after cerebral I/R

W Li, NC Suwanwela, S Patumraj - Microvascular research, 2016 - Elsevier
Background Oxidation, inflammation, and apoptosis are three critical factors for the
pathogenic mechanism of cerebral ischemia/reperfusion (I/R) injury. Curcumin exhibits …

Neuroprotection by curcumin: A review on brain delivery strategies

A Askarizadeh, GE Barreto, NC Henney… - International journal of …, 2020 - Elsevier
Neurodegenerative diseases are a major global public health concern in the elderly
population but therapeutic options are limited. Curcumin is a hydrophobic polyphenol …

Curcumin nanoformulations to combat aging-related diseases

M Mahjoob, U Stochaj - Ageing Research Reviews, 2021 - Elsevier
Aging increases the susceptibility to a diverse set of diseases and disorders, including
neurodegeneration, cancer, diabetes, and arthritis. Natural compounds are currently being …

pH-Responsive multifunctional theranostic rapamycin-loaded nanoparticles for imaging and treatment of acute ischemic stroke

Y Cheng, A Cheng, Y Jia, L Yang, Y Ning… - … Applied Materials & …, 2021 - ACS Publications
Stroke is the second leading cause of death globally and the most common cause of severe
disability. Several barriers need to be addressed more effectively to treat stroke, including …

[HTML][HTML] Poloxamer-chitosan-based Naringenin nanoformulation used in brain targeting for the treatment of cerebral ischemia

N Ahmad, R Ahmad, FJ Ahmad, W Ahmad… - Saudi Journal of …, 2020 - Elsevier
Objective Here, the aim is to improve the bioavailability of Naringenin (NRG) in brain and to
establish the highest remedial benefit from a novel anti-ischemic medicine ie NRG. Methods …