Snakebite envenoming is an important public health issue responsible for mortality and
severe morbidity. Where mortality is mainly caused by venom toxins that induce …

Secreted phospholipases A 2 (sPLA 2 s) participate in a very broad spectrum of biological
processes through their enzymatic activity and as ligands for membrane and soluble …

Snakebite envenoming remains a neglected tropical disease which poses severe health
hazard, especially for the rural inhabitants in Africa. In Nigeria, vipers are responsible for the …

Snake bite is a neglected disease that affects millions of people worldwide. WHO reported
approximately 5 million people are bitten by various species of snakes each year, resulting …

Snake venoms are primarily composed of proteins and peptides, and these toxins have
developed high selectivity to their biological targets. This makes venoms interesting for …

In Colombia, South America, there is a subspecies of the South American rattlesnake
Crotalus durissus, C. d. cumanensis, a snake of the Viperidae family, whose presence has …

Phospholipases A2 (PLA2) are enzymes acting on the cell membrane phospholipids
resulting in fatty acids and lysophospholipids and deconstructing the cell membrane. This …

Ly6/uPAR proteins regulate many essential functions in the nervous and immune systems
and epithelium. Most of these proteins contain single β-structural LU domains with three …

Snakebite envenomation is a serious health concern in tropical regions, resulting in high
mortality. The World Health Organization (WHO) has declared it a neglected tropical disease …

Crotoxin, a phospholipase A 2 (PLA 2) complex and the major Crotalus venom component,
is responsible for the main symptoms described in crotalic snakebite envenomings and a …