Cognitive decline in chronic diabetic patients is a less investigated topic. Diabetes and
obesity are among the modifiable risk factors for Alzheimer's disease (AD), the most …

The soluble receptor for advanced glycation end-products (sRAGE) has been classically
considered a sink for pro-inflammatory RAGE ligands and as such has been associated with …

Individuals with diabetes mellitus (DM) disclose a higher incidence and a poorer prognosis
of heart failure (HF) than non-diabetic people, even in the absence of other HF risk factors …

Since the 1980s, chronic kidney disease (CKD) affecting all ages has increased by almost
25%. This increase may be partially attributable to lifestyle changes and increased global …

Purpose Recent studies have suggested that metabolic factors (obesity, diabetes,
hypertension and dyslipidemia) and their clustering in metabolic syndrome (MetS) might be …

A robust and heterogenous secretory phenotype is a core feature of most senescent cells. In
addition to mediators of age‐related pathology, components of the senescence associated …

The discovery of the receptor for advanced glycation end-products (RAGE) set the stage for
the elucidation of important mechanisms underpinning diabetic complications. RAGE …

Blood oligosaccharides are attached to many proteins after translation, forming
glycoproteins. Glycosylation refers to an enzyme-mediated modification that alters protein …

Advanced glycation end products (AGEs) are mediators in the process of cellular
dysfunction in response to hyperglycemia. Numerous data indicate that the accumulation of …

Context Reduced bone material strength index (BMSi) and increased cortical porosity (CtPo)
have emerged as potentially contributing to fracture risk in type 2 diabetes mellitus (T2DM) …