Cell death has been subdivided into the categories apoptosis (Type I), autophagic cell death
(Type II), and necrosis (Type III). The boundary between Type I and II has never been …

Currently, the most effective treatment for end-stage liver fibrosis is liver transplantation;
however, transplantation is limited by a shortage of donor organs, surgical complications …

Although apoptosis and necrosis have distinct features, the identification and discrimination
of apoptotic and necrotic cell death in vitro is challenging. Immunocytological and …

Vitamin C (ASC) is well known as an outstanding antioxidant in animal tissues. This concept
is reviewed from a chemical standpoint, starting from a chemical view of radical reactions in …

Abstract Cisplatin, doxorubicin and fluorouracil (5-FU), drugs belonging to different chemical
classes, have been extensively used for chemotherapy of various cancers. Despite …

The hepatotoxicity of thioacetamide (TA) has been known since 1948. In rats, single doses
cause centrolobular necrosis accompanied by increases in plasma transaminases and …

In acute liver injury induced by the injection of CCl4, cell death has been attributed to the
necrosis of hepatocytes in the centrilobular area. In the present study, we re-examined the …

Apoptosis is a process of active cell death, distinct from necrosis and characterized by
specific morphological and biochemical features. Although the acute hepatotoxic effects of …

Apoptosis and necrosis are two distinct forms of cell death. Caspases are indispensable as
initiators and effectors of apoptotic cell death and are involved in many of the morphological …

The inner bark of cinnamon (Cinnamomum zeylanicum L.) is commonly used as a spice and
has also been widely employed in the treatment and prevention of disease. The aim of the …