Enteric nervous system: sensory transduction, neural circuits and gastrointestinal motility
NJ Spencer, H Hu - Nature reviews Gastroenterology & hepatology, 2020 - nature.com
The gastrointestinal tract is the only internal organ to have evolved with its own independent
nervous system, known as the enteric nervous system (ENS). This Review provides an …
nervous system, known as the enteric nervous system (ENS). This Review provides an …
Gut feelings: mechanosensing in the gastrointestinal tract
A Mercado-Perez, A Beyder - Nature Reviews Gastroenterology & …, 2022 - nature.com
The primary function of the gut is to procure nutrients. Synchronized mechanical activities
underlie nearly all its endeavours. Coordination of mechanical activities depends on …
underlie nearly all its endeavours. Coordination of mechanical activities depends on …
Gut microbiota-motility interregulation: insights from in vivo, ex vivo and in silico studies
The human gastrointestinal tract is home to trillions of microbes. Gut microbial communities
have a significant regulatory role in the intestinal physiology, such as gut motility. Microbial …
have a significant regulatory role in the intestinal physiology, such as gut motility. Microbial …
Interstitial cells of Cajal and human colon motility in health and disease
JD Huizinga, A Hussain… - American Journal of …, 2021 - journals.physiology.org
Our understanding of human colonic motility, and autonomic reflexes that generate motor
patterns, has increased markedly through high-resolution manometry. Details of the motor …
patterns, has increased markedly through high-resolution manometry. Details of the motor …
[HTML][HTML] PIEZO2 in somatosensory neurons controls gastrointestinal transit
The gastrointestinal tract is in a state of constant motion. These movements are tightly
regulated by the presence of food and help digestion by mechanically breaking down and …
regulated by the presence of food and help digestion by mechanically breaking down and …
Ca2+ dynamics in interstitial cells: foundational mechanisms for the motor patterns in the gastrointestinal tract
The gastrointestinal (GI) tract displays multiple motor patterns that move nutrients and
wastes through the body. Smooth muscle cells (SMCs) provide the forces necessary for GI …
wastes through the body. Smooth muscle cells (SMCs) provide the forces necessary for GI …
Spontaneous electrical activity and rhythmicity in gastrointestinal smooth muscles
KM Sanders - Smooth muscle spontaneous activity: Physiological …, 2019 - Springer
The gastrointestinal (GI) tract has multifold tasks of ingesting, processing, and assimilating
nutrients and disposing of wastes at appropriate times. These tasks are facilitated by several …
nutrients and disposing of wastes at appropriate times. These tasks are facilitated by several …
Listen to your gut: key concepts for bioengineering advanced models of the intestine
O Cameron, JF Neves, E Gentleman - Advanced Science, 2024 - Wiley Online Library
The intestine performs functions central to human health by breaking down food and
absorbing nutrients while maintaining a selective barrier against the intestinal microbiome …
absorbing nutrients while maintaining a selective barrier against the intestinal microbiome …
Functional intraregional and interregional heterogeneity between myenteric glial cells of the colon and duodenum in mice
L Seguella, JL McClain, G Esposito… - Journal of …, 2022 - Soc Neuroscience
Enteric glia are a unique population of peripheral neuroglia that regulate homeostasis in the
enteric nervous system (ENS) and intestinal functions. Despite existing in functionally …
enteric nervous system (ENS) and intestinal functions. Despite existing in functionally …
Identification of a rhythmic firing pattern in the enteric nervous system that generates rhythmic electrical activity in smooth muscle
NJ Spencer, TJ Hibberd, L Travis… - Journal of …, 2018 - Soc Neuroscience
The enteric nervous system (ENS) contains millions of neurons essential for organization of
motor behavior of the intestine. It is well established that the large intestine requires ENS …
motor behavior of the intestine. It is well established that the large intestine requires ENS …