A thorough understanding of optical properties of biological tissues is critical to effective
treatment planning for therapies such as photodynamic therapy (PDT). In the last two …

In the past decade, photoacoustic (PA) imaging has attracted a great deal of popularity as an
emergent diagnostic technology owing to its successful demonstration in both preclinical …

Melanoma diagnosis is clinically challenging: the accuracy of visual inspection by
dermatologists is highly variable and heavily weighted toward false positives. Even the …

Abstract Objective and Impact Statement. Molecular signatures are needed for early
diagnosis and improved treatment of metastatic melanoma. By high-resolution multimodal …

Changes in the amounts of cellular eumelanin and pheomelanin have been associated with
carcinogenesis. The goal of this work is to develop methods based on two-photon-excited …

In this paper, we propose a novel approach to discriminate malignant melanomas and
benign atypical nevi, since both types of melanocytic skin lesions have very similar …

More people die from melanoma after a stage I diagnosis than after a stage IV diagnosis,
because the tools available to clinicians do not readily identify which early-stage cancers …

Early detection and diagnosis is a must in secondary prevention of melanoma and other
cancerous lesions of the skin. In this work, we present an online, reservoir-based, non …

Optical spectroscopy has been intensively studied for cancer management in the past two
decades. This review paper first introduces the background of optical spectroscopy for …

Nonlinear photothermal microscopy, in which the intensity of the pump heating beam is
modulated at f and the photothermal signal is extracted from the probe beam with a lock-in …