DNA methylation is the most well studied of the epigenetic regulators in relation to
environmental exposures. To date, numerous studies have detailed the manner by which …

Environmental exposures, psychosocial stressors and nutrition are all potentially important
influences that may impact health outcomes directly or via interactions with the genome or …

Metal exposure is pervasive and not limited to sporadic poisoning events or toxic waste
sites. Hundreds of millions of people around the globe are affected by chronic metal …

Background: Exposure to inorganic and organic arsenic compounds is a major public health
problem that affects hundreds of millions of people worldwide. Exposure to arsenic is …

More than 200 million people in 70 countries are exposed to arsenic through drinking water.
Chronic exposure to this metalloid has been associated with the onset of many diseases …

Background Gestational age is often used as a proxy for developmental maturity by
clinicians and researchers alike. DNA methylation has previously been shown to be …

Background Epigenetic mechanisms, including methylation, can contribute to childhood
asthma. Identifying DNA methylation profiles in asthmatic patients can inform disease …

Studies conducted over the past eight years in Latin America (LA) have continued to
produce new knowledge regarding health impacts of arsenic (As) in drinking water. We …

Genome instability is a prerequisite for the development of cancer. It occurs when genome
maintenance systems fail to safeguard the genome's integrity, whether as a consequence of …

Background: Prenatal exposure to air pollution has been associated with childhood
respiratory disease and other adverse outcomes. Epigenetics is a suggested link between …