SCUBE2 regulates adherens junction dynamics and vascular barrier function during inflammation

YC Lin, YJ Chang, SS Gau, CM Lo… - Cardiovascular …, 2024 - academic.oup.com
Aims SCUBE2 (S ignal peptide-CUB-e pidermal growth factor-like domain-containing
protein 2) is a secreted or membrane-bound protein originally identified from endothelial …

SCUBE3 exerts a tumor-promoting effect in tongue squamous cell carcinoma by promoting CEBPA binding to the CCL2 promoter

M Zhu, Y Ma, W Wang, M Li, S Chen, F Liu, X Shi… - Molecular Cancer …, 2024 - AACR
Tongue squamous cell carcinoma (TSCC) is the main pathologic subtype of oral cancer, and
the current therapeutic effect is far from satisfactory. The signal peptide-CUB-EGF domain …

Plasma SCUBE2 As a Novel Biomarker Associates with Survival Outcomes in Patients with Sepsis-Associated Acute Kidney Injury

KH Lee, YC Lin, MT Tsai, CF Tu, SM Ou… - Journal of Microbiology …, 2024 - Elsevier
Background The adverse effects of sepsis-associated acute kidney injury (SA-AKI) highlight
the need for new biomarkers. Signal Peptide-Complement C1r/C1s, Uegf, Bmp1-Epidermal …

Biochemical study of ZNF76 rs10947540 and SCUBE3 rs1888822 single nucleotide polymorphisms in the Egyptian patients with systemic lupus Erythematosus

MF Ali Assar, EM Abd El Gayed… - … of Immunoassay and …, 2024 - Taylor & Francis
Systemic lupus erythematosus (SLE) is a common autoimmune disease marked by the
formation of apoptotic debris and the presence of autoantibodies that target nuclear …

Unravelling the molecular landscape of endometrial cancer subtypes: insights from multi-omics analysis

Y Shen, Y Tian, J Ding, Z Chen, R Zhao… - … Journal of Surgery, 2024 - journals.lww.com
Background: Endometrial cancer (EC) as one of the most common gynecologic
malignancies is increasing in incidence during the past 10 years. Genome-Wide Association …

[HTML][HTML] Inflammation: Complexity and significance of cellular and molecular responses

S Özdemir - Journal of Acute Disease, 2024 - journals.lww.com
Inflammation is a multifaceted cellular and molecular response triggered by injury, infection,
or various pathological conditions. Serving as a protective defense mechanism, the …

Efficient fine-tuning of endothelial gene expression by Y to Phe mutation in the VE-cadherin gene

O GARNIER, F JEANNERET, A DURAND, A FERTIN… - bioRxiv, 2024 - biorxiv.org
We aimed at understanding whether the site Y685 of VE-cadherin triggers epigenetic
programming in vivo. Using our knock-in mice carrying the Y685F VE-cadherin mutation …

SCUBE in human diseases: A systematic review

H Ali - Marmara Medical Journal, 2024 - dergipark.org.tr
The involvement of the Signal peptide-complement components of C1r/C1s, the sea urchin
Uegf and Bone Morphogenetic Protein (CUB) domain-Epidermal Growth Factor (EGF) …

Peran Epigallocatechin-3-gallate (EGCG) dalam Menghambat Perkembangan Fibrosis Pleura, Ekspresi SCUBE3, dan Transforming Growth Factror-β (TGF-β) pada …

M Riendra, NI Lipoeto, RS Rita… - Intisari Sains …, 2024 - smtpauth.isainsmedis.id
Empyema in the lungs can cause pulmonary fibrosis which can cause restrictions in the
movement of the lung parenchyma. Epigallocatechin-3-gallate (EGCG) is the most active …

SCUBE in human diseases: A systematic review.

ALI Hirowati - Marmara Medical Journal, 2024 - search.ebscohost.com
The involvement of the Signal peptide-complement components of C1r/C1s, the sea urchin
Uegf and Bone Morphogenetic Protein (CUB) domain-Epidermal Growth Factor (EGF) …