[HTML][HTML] Trends in amorphous solid dispersion drug products approved by the US Food and Drug Administration between 2012 and 2023

DE Moseson, TB Tran, B Karunakaran… - International Journal of …, 2024 - Elsevier
Abstract Forty-eight (48) drug products (DPs) containing amorphous solid dispersions
(ASDs) have been approved by the US Food and Drug Administration in the 12-year period …

[HTML][HTML] Use of Poly (vinyl alcohol) in Spray-Dried Dispersions: Enhancing Solubility and Stability of Proteolysis Targeting Chimeras

L Mareczek, LK Mueller, L Halstenberg, TM Geiger… - Pharmaceutics, 2024 - mdpi.com
PROTACs, proteolysis targeting chimeras, are bifunctional molecules inducing protein
degradation through a unique proximity-based mode of action. While offering several …