[HTML][HTML] Hypoxia, metabolic reprogramming, and drug resistance in liver cancer

MHR Bao, CCL Wong - Cells, 2021 - mdpi.com
Hypoxia, low oxygen (O2) level, is a hallmark of solid cancers, especially hepatocellular
carcinoma (HCC), one of the most common and fatal cancers worldwide. Hypoxia …

[HTML][HTML] Travelling under pressure-hypoxia and shear stress in the metastatic journey

ES Ildiz, A Gvozdenovic, WJ Kovacs… - Clinical & Experimental …, 2023 - Springer
Cancer cell invasion, intravasation and survival in the bloodstream are early steps of the
metastatic process, pivotal to enabling the spread of cancer to distant tissues. Circulating …

[HTML][HTML] Tumour response to hypoxia: understanding the hypoxic tumour microenvironment to improve treatment outcome in solid tumours

KJA Bigos, CG Quiles, S Lunj, DJ Smith… - Frontiers in …, 2024 - frontiersin.org
Hypoxia is a common feature of solid tumours affecting their biology and response to
therapy. One of the main transcription factors activated by hypoxia is hypoxia-inducible …

HIF‐1α Regulates the Progression of Cervical Cancer by Targeting YAP/TAZ

A Abudoukerimu, A Hasimu… - Journal of …, 2022 - Wiley Online Library
Cervical carcinoma is one of the serious pernicious cancers that influence women's health.
Invasion and metastasis are the chief reason of poor prognosis of cervical carcinoma …

[HTML][HTML] Association of FOXO3 expression with tumor pathogenesis, prognosis and clinicopathological features in hepatocellular carcinoma: a systematic review with …

F Fondevila, P Fernandez-Palanca, C Mendez-Blanco… - Cancers, 2021 - mdpi.com
Simple Summary Liver cancer, mainly represented by hepatocellular carcinoma (HCC),
constitutes the current third leading cause of tumor-associated death worldwide. Therefore …

[HTML][HTML] Neuropilin-1 as a potential biomarker of prognosis and invasive-related parameters in liver and colorectal cancer: A systematic review and meta-analysis of …

P Fernández-Palanca, T Payo-Serafín, F Fondevila… - Cancers, 2022 - mdpi.com
Simple Summary Neuropilin-1 (NRP1) is a transmembrane protein which has had recently
increased interest from cancer researchers. Liver cancer and colorectal cancer (CRC) are …

NK cell immunometabolism as target for liver cancer therapy

J Wang, X Liu, T Jin, Y Cao, Y Tian, F Xu - International …, 2022 - Elsevier
Natural killer (NK) cells are being used effectively as a potential candidate in tumor
immunotherapy. However, the migration and transport of NK cells to solid tumors is …

[HTML][HTML] Autophagy-related chemoprotection against sorafenib in human hepatocarcinoma: Role of FOXO3 upregulation and modulation by regorafenib

F Fondevila, C Méndez-Blanco… - International Journal of …, 2021 - mdpi.com
Early acquisition of sorafenib resistance is responsible for the dismal prognosis of advanced
hepatocarcinoma (HCC). Autophagy, a catabolic process involved in liver homeostasis, has …

[HTML][HTML] Hypoxia‑inducible factor‑1α: A critical target for inhibiting the metastasis of hepatocellular carcinoma

H Chen, J Chen, H Yuan, X Li, W Li - Oncology Letters, 2022 - spandidos-publications.com
Metastasis is one of the major reasons for patient mortality in hepatocellular carcinoma
(HCC), and the progression of HCC to a metastatic state depends on the local …

Efficacy and safety of the arsenic trioxide/lipiodol emulsion in the transcatheter arterial chemoembolization combined with apatinib in the treatment of advanced …

Z Li, Q Chen, W Zhang, G Si, J Li… - Canadian Journal of …, 2021 - Wiley Online Library
Purpose. The goal of this study was to assess the clinical efficacy and safety of the arsenic
trioxide (ATO)/lipiodol emulsion in the transcatheter arterial chemoembolization (TACE) …