Trypanosoma cruzi, the causative agent of Chagas disease, is an obligatory intracellular
parasite with a digenetic life cycle. Due to the variety of host environments, it faces several …

Chagas disease is one of the most important endemic diseases in Latin America, caused by
Trypanosoma cruzi. The drugs used for the treatment of this disease, nifurtimox and …

Chagas disease (CD) is a worldwide public health problem, and the drugs available for its
treatment have severe limitations. Red propolis is a natural extract known for its high content …

Acetylsalicylic acid (ASA) is one of the most commonly used drugs in the world. It derives
from the extract of white willow bark, whose therapeutic potential was known in Egypt since …

Chagas disease is a parasitic infection caused by the intracellular protozoan Trypanosoma
cruzi. Chronic Chagas cardiomyopathy (CCC) is the most severe manifestation of the …

Objectives Even though the use of combined drugs has been proved to be effective in other
chronic infections, assessment of combined treatment of antiparasitic drugs in human …

Chagas' disease, produced by Trypanosoma cruzi, affects more than 8 million people,
producing approximately 10,000 deaths each year in Latin America. Migration of people …

Pathogenic trypanosomatids (Trypanosoma cruzi, Trypanosoma brucei, and Leishmania
spp.) are protozoan parasites that cause neglected diseases affecting millions of people in …

Chagas' disease, or American trypanosomosiasis, has been the most relevant illness
produced by protozoa in Latin America. Synthetic medicinal chemistry efforts have provided …

Trypanosoma cruzi is the causal agent of Chagas Disease that is endemic in Latin
American, afflicting more than ten million people approximately. This disease has two …