Mass spectrometry-based biomolecular analyses have become permanent fixtures of
academic, industrial, and clinical research settings. The rise in utilization of mass …

Amyloid fibrils, insoluble β‐sheets structures that arise from protein misfolding, are
associated with several neurodegenerative disorders. Many small molecules have been …

Abstract β‐amyloid (Aβ) is one of the important biomarkers for diagnosing Alzheimer's
disease (AD). Many near‐infrared probes based on the donor‐π‐acceptor structure have …

Hyperactivated glycolysis is a metabolic hallmark of most cancer cells. Although sporadic
information has revealed that glycolytic metabolites possess nonmetabolic functions as …

Stereochemical modifications (SCMs), mostly present in the form of d-amino acid
substitution, have been increasingly identified from a wide range of neuropeptides and …

Genetically encoding proximal-reactive unnatural amino acids (PrUaas), such as
fluorosulfate-l-tyrosine (FSY), into natural proteins of interest (POI) confer the POI with the …

Fast photochemical oxidation of proteins (FPOP) is a hydroxyl radical footprinting approach
whereby radicals, produced by UV laser photolysis of hydrogen peroxide, induce oxidation …

Characterization of antibody binding epitopes is an important factor in therapeutic drug
discovery, as the binding site determines and drives antibody pharmacology and …

Structural biology is entering an exciting time where many new high‐resolution structures of
large complexes and membrane proteins (MPs) are determined regularly. These advances …

The dynamic associations of transient protein–protein interactions (PPIs) are critical
mediators of myriad biochemical processes. These specific, low-affinity interactions are often …