To overcome the shortcomings of conventional dosage forms, targeted and modified drug
delivery system came into existence. This was the time when a novel drug delivery system …

Introduced in the late 1950s, polyenes represent the oldest family of antifungal drugs. The
discovery of amphotericin B and its therapeutic uses is considered one of the most important …

The high incidence of fungal infections has become a worrisome public health issue, having
been aggravated by an increase in host predisposition factors. Despite all the drugs …

Invasive fungal infections (IFIs) represent a growing public concern for clinicians to manage
in many medical settings, with substantial associated morbidities and mortalities. Among …

Among the different synthetic polymers developed for biomedical applications, poly (lactic-
co-glycolic acid)(PLGA) has attracted considerable attention because of its excellent …

Treatment modalities for systemic mycoses are still limited. Currently, the main antifungal
therapeutics include polyenes, azoles, and echinocandins. However, even in the setting of …

There is a growing interest in the development of organic nanomaterials for biomedical
applications. An increasing number of studies focus on the uses of nanomaterials with …

Invasive mycoses are a major problem for immunocompromised individuals and patients in
intensive care units. Morbidity and mortality rates of these infections are high because of late …

Amphotericin B (AMB) is used most commonly in severe systemic life-threatening fungal
infections. There is currently an unmet need for an efficacious (AMB) formulation amenable …

Diseases caused by fungi can occur in healthy people, but immunocompromised patients
are the major risk group for invasive fungal infections. Cases of fungal resistance and the …