Biological research and self-driving labs in deep space supported by artificial intelligence

LM Sanders, RT Scott, JH Yang, AA Qutub… - Nature Machine …, 2023 - nature.com
Abstract Space biology research aims to understand fundamental spaceflight effects on
organisms, develop foundational knowledge to support deep space exploration and …

Space, the final frontier: A critical review of recent experiments performed in microgravity

JP Vandenbrink, JZ Kiss - Plant Science, 2016 - Elsevier
Abstract Space biology provides an opportunity to study plant physiology and development
in a unique microgravity environment. Recent space studies with plants have provided …

Mission architecture using the SpaceX starship vehicle to enable a sustained human presence on Mars

JL Heldmann, MM Marinova, DSS Lim, D Wilson… - New Space, 2022 - liebertpub.com
A main goal of human space exploration is to develop humanity into a multi-planet species
where civilization extends beyond planet Earth. Establishing a self-sustaining human …

Spaceflight induces novel regulatory responses in Arabidopsis seedling as revealed by combined proteomic and transcriptomic analyses

CPS Kruse, AD Meyers, P Basu, S Hutchinson… - BMC Plant …, 2020 - Springer
Background Understanding of gravity sensing and response is critical to long-term human
habitation in space and can provide new advantages for terrestrial agriculture. To this end …

[HTML][HTML] Plant biology for space exploration–Building on the past, preparing for the future

E Kordyum, KH Hasenstein - Life sciences in space research, 2021 - Elsevier
A review of past insights of space experiments with plants outlines basic space and gravity
effects as well as gene expression. Efforts to grow plants in space gradually incorporated …

Glycome profiling and immunohistochemistry uncover changes in cell walls of Arabidopsis thaliana roots during spaceflight

J Nakashima, S Pattathil, U Avci, S Chin… - npj …, 2023 - nature.com
A large and diverse library of glycan-directed monoclonal antibodies (mAbs) was used to
determine if plant cell walls are modified by low-gravity conditions encountered during …

Genetic dissection of the Arabidopsis spaceflight transcriptome: Are some responses dispensable for the physiological adaptation of plants to spaceflight?

AL Paul, NJ Sng, AK Zupanska, A Krishnamurthy… - PLoS …, 2017 - journals.plos.org
Experimentation on the International Space Station has reached the stage where repeated
and nuanced transcriptome studies are beginning to illuminate the structural and metabolic …

Root Skewing-Associated Genes Impact the Spaceflight Response of Arabidopsis thaliana

B Califar, NJ Sng, A Zupanska, AL Paul… - Frontiers in Plant …, 2020 - frontiersin.org
The observation that plant roots skew in microgravity recently refuted the long-held
conviction that skewing was a gravity-dependent phenomenon. Further, spaceflight root …

Fusarium oxysporum as an Opportunistic Fungal Pathogen on Zinnia hybrida Plants Grown on board the International Space Station

AC Schuerger, BS Amaradasa, NS Dufault… - Astrobiology, 2021 - liebertpub.com
A plant production system called Veggie was launched to the International Space Station
(ISS) in 2014. In late 2015, during the growth of Zinnia hybrida cv.'Profusion'in the Veggie …

Epigenomics in an extraterrestrial environment: organ-specific alteration of DNA methylation and gene expression elicited by spaceflight in Arabidopsis thaliana

M Zhou, NJ Sng, CE LeFrois, AL Paul, RJ Ferl - BMC genomics, 2019 - Springer
Background Plants adapted to diverse environments on Earth throughout their evolutionary
history, and developed mechanisms to thrive in a variety of terrestrial habitats. When plants …