Nur77 serves as a molecular brake of the metabolic switch during T cell activation to restrict autoimmunity
M Liebmann, S Hucke, K Koch… - Proceedings of the …, 2018 - National Acad Sciences
T cells critically depend on reprogramming of metabolic signatures to meet the bioenergetic
demands during activation and clonal expansion. Here we identify the transcription factor …
demands during activation and clonal expansion. Here we identify the transcription factor …
Cytokine regulation of immune tolerance
J Wu, A Xie, W Chen - Burns & trauma, 2014 - academic.oup.com
The immune system provides defenses against invading pathogens while maintaining
immune tolerance to self-antigens. This immune homeostasis is harmonized by the direct …
immune tolerance to self-antigens. This immune homeostasis is harmonized by the direct …
Thymic stromal lymphopoietin signaling in CD4+ T cells is required for TH2 memory
Background Thymic stromal lymphopoietin (TSLP) is a key factor in the development of
allergic asthma. Numbers of TH 2 memory cells gradually increase in allergic patients with …
allergic asthma. Numbers of TH 2 memory cells gradually increase in allergic patients with …
[HTML][HTML] Anti-TCRβ mAb induces long-term allograft survival by reducing antigen-reactive T cells and sparing regulatory T cells
Y Miyahara, M Khattar, PM Schroder… - American Journal of …, 2012 - Elsevier
TCR specific antibodies may modulate the TCR engagement with antigen–MHC complexes,
and in turn regulate in vivo T cell responses to alloantigens. Herein, we found that in vivo …
and in turn regulate in vivo T cell responses to alloantigens. Herein, we found that in vivo …
[PDF][PDF] Rola sygnałów aktywacyjnych i cytokin w powstawaniu in vitro pochodzących z grasicy limfocytów T regulatorowych
AM Bieńkowska - repozytorium.uw.edu.pl
Głównymi funkcjami układu odpornościowego są obrona organizmu przed patogenami,
eliminacja komórek starych, martwych i nowotworowych oraz utrzymanie tolerancji na …
eliminacja komórek starych, martwych i nowotworowych oraz utrzymanie tolerancji na …
[图书][B] Targeting effector CD4 T cell developmental plasticity for improving vaccine design
MF Goldberg - 2013 - search.proquest.com
Naive CD4 T cells have remarkable developmental plasticity and can differentiate into TH 1,
TH 2, TH 17, inducible regulatory T cells (iT reg), and T follicular helper cells (T fH) subsets …
TH 2, TH 17, inducible regulatory T cells (iT reg), and T follicular helper cells (T fH) subsets …