How to optimize the use of blood cultures for the diagnosis of bloodstream infections? A state-of-the art

B Lamy, S Dargère, MC Arendrup, JJ Parienti… - Frontiers in …, 2016 - frontiersin.org
Bloodstream infection (BSI) is a major cause of death in developed countries and the
detection of microorganisms is essential in managing patients. Despite major progress has …

The cost-effectiveness of rapid diagnostic testing for the diagnosis of bloodstream infections with or without antimicrobial stewardship

EE Pliakos, N Andreatos, F Shehadeh… - Clinical microbiology …, 2018 - Am Soc Microbiol
Bloodstream infections are associated with considerable morbidity and health care costs.
Molecular rapid diagnostic tests (mRDTs) are a promising complement to conventional …

Development of a chitosan-based wound dressing with improved hemostatic and antimicrobial properties

SY Ong, J Wu, SM Moochhala, MH Tan, J Lu - Biomaterials, 2008 - Elsevier
Hemorrhage remains a leading cause of early death after trauma, and infectious
complications in combat wounds continue to challenge caregivers. Although chitosan …

Does this adult patient with suspected bacteremia require blood cultures?

B Coburn, AM Morris, G Tomlinson, AS Detsky - Jama, 2012 - jamanetwork.com
Context Clinicians order blood cultures liberally among patients in whom bacteremia is
suspected, though a small proportion of blood cultures yield true-positive results. Ordering …

Direct identification of bacteria in positive blood culture bottles by matrix-assisted laser desorption ionisation time-of-flight mass spectrometry

B La Scola, D Raoult - PloS one, 2009 - journals.plos.org
Background With long delays observed between sampling and availability of results, the
usefulness of blood cultures in the context of emergency infectious diseases has recently …

Best practices of blood cultures in low-and middle-income countries

S Ombelet, B Barbé, D Affolabi, JB Ronat… - Frontiers in …, 2019 - frontiersin.org
Bloodstream infections (BSI) have a substantial impact on morbidity and mortality worldwide.
Despite scarcity of data from many low-and middle-income countries (LMICs), there is …

Procalcitonin levels predict bacteremia in patients with community-acquired pneumonia: a prospective cohort trial

F Müller, M Christ-Crain, T Bregenzer, M Krause… - Chest, 2010 - Elsevier
Background Guidelines recommend blood culture sampling from hospitalized patients with
suspected community-acquired pneumonia (CAP). However, the yield of true-positive results …

Blood culture utilization in the hospital setting: a call for diagnostic stewardship

V Fabre, KC Carroll, SE Cosgrove - Journal of clinical …, 2022 - Am Soc Microbiol
There has been significant progress in detection of bloodstream pathogens in recent
decades with the development of more sensitive automated blood culture detection systems …

Neutrophil to lymphocyte count ratio as an early indicator of blood stream infection in the emergency department

R Lowsby, C Gomes, I Jarman, P Lisboa… - Emergency medicine …, 2015 - emj.bmj.com
Objectives Early identification of patients with blood stream infection (BSI), especially
bacteraemia, is important as prompt treatment improves outcome. The initial stages of …

Best clinical practice: blood culture utility in the emergency department

B Long, A Koyfman - The Journal of emergency medicine, 2016 - Elsevier
Background Bacteremia affects 200,000 patients per year, with the potential for significant
morbidity and mortality. Blood cultures are considered the most sensitive method for …