Recent advances in molecular and immunological diagnostic platform for virus detection: A review

KTL Trinh, HDK Do, NY Lee - Biosensors, 2023 - mdpi.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused an ongoing
coronavirus disease (COVID-19) outbreak and a rising demand for the development of …

Advances in Simple, Rapid, and Contamination-Free Instantaneous Nucleic Acid Devices for Pathogen Detection

Y Wang, C Wang, Z Zhou, J Si, S Li, Y Zeng, Y Deng… - Biosensors, 2023 - mdpi.com
Pathogenic pathogens invade the human body through various pathways, causing damage
to host cells, tissues, and their functions, ultimately leading to the development of diseases …

Ultra‐Fast Single‐Nucleotide‐Variation Detection Enabled by Argonaute‐Mediated Transistor Platform

D Kong, S Zhang, M Guo, S Li, Q Wang… - Advanced …, 2024 - Wiley Online Library
Abstract “Test‐and‐go” single‐nucleotide variation (SNV) detection within several minutes
remains challenging, especially in low‐abundance samples, since existing methods face a …

Sensitive and quantitative point-of-care HIV viral load quantification from blood using a power-free plasma separation and portable magnetofluidic polymerase chain …

HT Ngo, M Jin, AY Trick, FE Chen, L Chen… - Analytical …, 2022 - ACS Publications
Point-of-care (POC) HIV viral load (VL) tests are needed to enhance access to HIV VL
testing in low-and middle-income countries (LMICs) and to enable HIV VL self-testing at …

Filtration-assisted magnetofluidic cartridge platform for HIV RNA detection from blood

AY Trick, HT Ngo, AH Nambiar, MM Morakis, FE Chen… - Lab on a Chip, 2022 - pubs.rsc.org
The ability to detect and quantify HIV RNA in blood is essential to sensitive detection of
infections and monitoring viremia throughout treatment. Current options for point-of-care HIV …

Emerging Multiplex Nucleic Acid Diagnostic Tests for Combating COVID-19

P Akarapipad, E Bertelson, A Pessell, TH Wang… - Biosensors, 2022 - mdpi.com
The COVID-19 pandemic caused by SARS-CoV-2 has drawn attention to the need for fast
and accurate diagnostic testing. Concerns from emerging SARS-CoV-2 variants and other …

Isotope-encoded tetrahedral DNA for multiple SARS-CoV-2 variant diagnosis

Z Li, J Zhou, C Wang, R Liu, J Hu, Y Lv - Chemical Science, 2023 - pubs.rsc.org
The evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has posed
an unprecedented demand for accurate and cost-effective diagnostic assays to discriminate …

Machine learning-assisted real-time polymerase chain reaction and high-resolution melt analysis for SARS-CoV-2 variant identification

S Promja, J Puenpa, T Achakulvisut… - Analytical …, 2023 - ACS Publications
Since the declaration of COVID-19 as a pandemic in early 2020, multiple variants of the
severe acute respiratory syndrome-related coronavirus (SARS-CoV-2) have been detected …

Numerical characterization and optimization of the acoustic device for heterogeneous immunoassays

Y Meng, Y Wu - Microfluidics and Nanofluidics, 2023 - Springer
In the context of the COVID-19 epidemic, enhancing the transport of analyte to a sensor
surface is crucial for rapid detection of biomolecules, since common conditions including low …

Point-of-care system for rapid real-time detection of SARS-CoV-2 virus based on commercially available Arduino platforms

H Van Ngoc, TL Quyen, AC Vinayaka… - … in Bioengineering and …, 2022 - frontiersin.org
The COVID-19 pandemic emphasized the importance of rapid, portable, and on-site testing
technologies necessary for resource-limited settings for effective testing and screening to …