Cancer therapy has been characterized throughout history by ups and downs, not only due
to the ineffectiveness of treatments and side effects, but also by hope and the reality of …

Regenerative medicine aims to create functional tissue replacements, typically through
creating a controlled environment that promotes and directs the differentiation of stem or …

Biotechnology, Second Edition approaches modern biotechnology from a molecular basis,
which has grown out of increasing biochemical understanding of genetics and physiology …

Numerous preclinical studies have demonstrated the efficacy of viral gene delivery vectors,
and recent clinical trials have shown promising results. However, the tight control of …

In the last few years, considerable progress has been made in the synthesis of C-glycosides.
Despite its challenging chemistry, due to its versatility, C-glycosides play a pivotal role in …

Spatiotemporal control of transgene expression is of paramount importance in gene therapy.
Here, we demonstrate the use of magnetic resonance temperature imaging (MRI)-guided …

The ability to genetically modify pigs has enabled scientists to create pigs that are beneficial
to humans in ways that were previously unimaginable. Improvements in the methods to …

Nuclear factor (NF)-κB is regarded as one of the most important transcription factors and
plays an essential role in the transcriptional activation of pro-inflammatory cytokines, cell …

Numerous studies have demonstrated the efficacy of the Adeno-Associated Virus (AAV)-
based gene delivery platform in vivo. The control of transgene expression in many protocols …

Site-specific drug delivery and targeting attracts much research interest from both academia
and industry, but because of the many challenges faced in the development of these …