The 24-hour molecular landscape after exercise in humans reveals MYC is sufficient for muscle growth

S Edman, RG Jones III, PR Jannig… - EMBO …, 2024 - embopress.org
A detailed understanding of molecular responses to a hypertrophic stimulus in skeletal
muscle leads to therapeutic advances aimed at promoting muscle mass. To decode the …

[HTML][HTML] The 24-Hour Time Course of Integrated Molecular Responses to Resistance Exercise in Human Skeletal Muscle Implicates MYC as a Hypertrophic Regulator …

S Edman, RG Jones III, PR Jannig… - bioRxiv, 2024 - ncbi.nlm.nih.gov
Molecular control of recovery after exercise in muscle is temporally dynamic. A time course
of biopsies around resistance exercise (RE) combined with-omics is necessary to better …

Exercise, disease state and sex influence the beneficial effects of Fn14-depletion on survival and muscle pathology in the SOD1G93A amyotrophic lateral sclerosis …

G Hazell, E McCallion, N Ahlskog, ER Sutton, M Okoh… - Skeletal Muscle, 2024 - Springer
Background Amyotrophic lateral sclerosis (ALS) is a devastating and incurable
neurodegenerative disease. Accumulating evidence strongly suggests that intrinsic muscle …

Uremia Impedes Skeletal Myocyte Myomixer Expression and Fusogenic Activity: Implication for Uremic Sarcopenia

T Higashihara, M Odawara, H Nishi… - The American Journal of …, 2024 - Elsevier
In patients with chronic kidney disease (CKD), skeletal muscle mass and function are known
to occasionally decline. However, the muscle regeneration and differentiation process in …

[HTML][HTML] LncRNA GTL2 regulates myoblast proliferation and differentiation via the PKA-CREB pathway in Duolang sheep

Q Chen, JJ Bao, HC Zhang, C Huang… - Zoological …, 2024 - pmc.ncbi.nlm.nih.gov
Long non-coding RNAs (lncRNAs), which are RNA molecules longer than 200 nucleotides
that do not encode proteins, are implicated in a variety of biological processes, including …

Fn14 signaling regulates satellite cell self-renewal and expansion during adult skeletal muscle repair

M Tomaz Da Silva, AS Joshi, A Kumar - bioRxiv, 2024 - biorxiv.org
Skeletal muscle regeneration in adults is predominantly driven by satellite cells. Loss of
satellite cell pool and function leads to skeletal muscle wasting in many conditions and …

Genomic insights into the successful invasion of the avian vampire fly (Philornis downsi) in the Galápagos Islands

A Basnet, C Palacios, H Meng, D Nakhwa, T Farmer… - bioRxiv, 2024 - biorxiv.org
Invasive species disrupt island ecosystems, posing significant threats to native species. The
avian vampire fly (Philornis downsi), introduced into the Galapagos Islands, has become a …