Unlocking the potential of mesoporous silica nanoparticles in breast cancer treatment
Breast cancer is the most common cancer among women and is typically managed through
surgery, radiation therapy, and chemotherapy. However, chemotherapy drugs often lack …
surgery, radiation therapy, and chemotherapy. However, chemotherapy drugs often lack …
[HTML][HTML] Lipid polymer hybrid nanoparticles: a custom-tailored next-generation approach for cancer therapeutics
Lipid-based polymeric nanoparticles are the highly popular carrier systems for cancer drug
therapy. But presently, detailed investigations have revealed their flaws as drug delivery …
therapy. But presently, detailed investigations have revealed their flaws as drug delivery …
[HTML][HTML] Application of aptamer-drug delivery system in the therapy of breast cancer
R Fan, X Tao, X Zhai, Y Zhu, Y Li, Y Chen… - Biomedicine & …, 2023 - Elsevier
Despite significant treatment advances, breast cancer remains the leading cause of cancer
death in women. From the current treatment situation, in addition to developing …
death in women. From the current treatment situation, in addition to developing …
[HTML][HTML] Advanced cancer targeting using aptamer functionalized nanocarriers for site-specific cargo delivery
The non-specificity of standard anticancer therapies has profound detrimental
consequences in clinical treatment. Therapeutic specificity can be precisely achieved using …
consequences in clinical treatment. Therapeutic specificity can be precisely achieved using …
Aptamers against cancer drug resistance: Small fighters switching tactics in the face of defeat
M Sanati, AR Afshari, SS Ahmadi, P Kesharwani… - … et Biophysica Acta (BBA …, 2023 - Elsevier
Discovering novel cancer therapies has attracted extreme interest in the last decade. In this
regard, multidrug resistance (MDR) to chemotherapies is a key challenge in cancer …
regard, multidrug resistance (MDR) to chemotherapies is a key challenge in cancer …
A comprehensive review of small interfering RNAs (siRNAs): mechanism, therapeutic targets, and delivery strategies for cancer therapy
J Zhang, B Chen, C Gan, H Sun, J Zhang… - International Journal of …, 2023 - Taylor & Francis
Small interfering RNA (siRNA) delivery by nanocarriers has been identified as a promising
strategy in the study and treatment of cancer. Short nucleotide sequences are synthesized …
strategy in the study and treatment of cancer. Short nucleotide sequences are synthesized …
[HTML][HTML] Recent advances in mesoporous silica nanoparticles delivering siRNA for cancer treatment
X Xie, T Yue, W Gu, WY Cheng, L He, WY Ren, F Li… - Pharmaceutics, 2023 - mdpi.com
Silencing genes using small interfering (si) RNA is a promising strategy for treating cancer.
However, the curative effect of siRNA is severely constrained by low serum stability and cell …
However, the curative effect of siRNA is severely constrained by low serum stability and cell …
Nanocarriers for delivering nucleic acids and chemotherapeutic agents as combinational approach: Challenges, clinical progress, and unmet needs
Cancer is the second leading cause of death after heart disease. It forms clusters of
immature cells, spreads through metastasis, and invades normal tissue. Chemotherapeutic …
immature cells, spreads through metastasis, and invades normal tissue. Chemotherapeutic …
TfR Aptamer-functionalized MSNs for enhancing targeted cellular uptake and therapy of cancer cells
J Zhang, J Shang, X Tang, X Xu - ACS omega, 2023 - ACS Publications
Mesoporous silica nanoparticles (MSNs), as novel nanocarriers for drug delivery in cancer
treatment, have attracted widespread concern because of their rich pore structure, large …
treatment, have attracted widespread concern because of their rich pore structure, large …
Stimuli‐Responsive Aptamer‐Drug Conjugates for Targeted Drug Delivery and Controlled Drug Release
S Zhu, H Gao, W Li, X He, P Jiang, F Xu… - Advanced …, 2024 - Wiley Online Library
Chemotherapy has been widely used for cancer therapy but with unsatisfied efficacy, mainly
due to the inefficient delivery of anticancer agents. Among the critical “five steps” drug …
due to the inefficient delivery of anticancer agents. Among the critical “five steps” drug …