Therapeutic drug monitoring (TDM) and model‐informed precision dosing (MIPD) have
evolved as important tools to inform rational dosing of antibiotics in individual patients with …

Tuberculosis remains the world's leading cause of death from an infectious disease,
responsible for an estimated 1 674 000 deaths annually. WHO estimated 600 000 cases of …

Background: The American Thoracic Society, US Centers for Disease Control and
Prevention, European Respiratory Society, and Infectious Diseases Society of America …

Background Improved genetic understanding of Mycobacterium tuberculosis (MTB)
resistance to novel and repurposed anti-tubercular agents can aid the development of rapid …

Antimicrobial resistance is one of the greatest challenges of the 21st century. Evaluation of
the public health burden of antimicrobial resistance, which is needed to drive policy …

The World Health Organization (WHO) recommends that countries implement
pharmacovigilance and collect information on active drug safety monitoring (aDSM) and …

Drug-resistant tuberculosis (DR-TB) remains a global crisis due to the increasing incidence
of drug-resistant forms of the disease, gaps in detection and prevention, models of care, and …

Tuberculosis (TB) is still the number one cause of death due to an infectious disease.
Pharmacokinetics and pharmacodynamics of anti-TB drugs are key in the optimization of TB …

Abstract Background We evaluated Nix-TB trial data (NCT02333799, N= 109) to provide
dosing recommendations to potentially minimize linezolid toxicity in patients with extensively …

Tuberculosis (TB) elimination requires innovative approaches. The new Global Tuberculosis
Network (GTN) aims to conduct research on key unmet therapeutic and diagnostic needs in …