Deleterious variation in natural populations and implications for conservation genetics

J Robinson, CC Kyriazis, SC Yuan… - Annual review of …, 2023 - annualreviews.org
Deleterious mutations decrease reproductive fitness and are ubiquitous in genomes. Given
that many organisms face ongoing threats of extinction, there is interest in elucidating the …

How can genomics help or hinder wildlife conservation?

TL Schmidt, JA Thia, AA Hoffmann - Annual Review of Animal …, 2024 - annualreviews.org
Genomic data are becoming increasingly affordable and easy to collect, and new tools for
their analysis are appearing rapidly. Conservation biologists are interested in using this …

Phylogenomics of the world's otters

V de Ferran, HV Figueiró, F de Jesus Trindade… - Current Biology, 2022 - cell.com
Comparative whole-genome analyses hold great power to illuminate commonalities and
differences in the evolution of related species that share similar ecologies. The mustelid …

The genomic footprint of whaling and isolation in fin whale populations

SF Nigenda-Morales, M Lin… - Nature …, 2023 - nature.com
Twentieth century industrial whaling pushed several species to the brink of extinction, with
fin whales being the most impacted. However, a small, resident population in the Gulf of …

Using computational simulations to model deleterious variation and genetic load in natural populations

CC Kyriazis, JA Robinson… - The American …, 2023 - journals.uchicago.edu
Deleterious genetic variation is abundant in wild populations, and understanding the
ecological and conservation implications of such variation is an area of active research …

[PDF][PDF] Genomic underpinnings of population persistence in Isle Royale moose

CC Kyriazis, AC Beichman, KE Brzeski… - Molecular biology …, 2023 - academic.oup.com
Island ecosystems provide natural laboratories to assess the impacts of isolation on
population persistence. However, most studies of persistence have focused on a single …

Insights Gained from Including People in Our Models of Nature and Modes of Science

AK Salomon, IainMcKechnie - Annual Review of Marine Science, 2024 - annualreviews.org
Across the natural sciences, humans are typically conceptualized as external disruptors of
nature rather than adaptable components of it. Historical evidence, however, challenges this …

Using computational simulations to quantify genetic load and predict extinction risk

CC Kyriazis, JA Robinson, KE Lohmueller - BioRxiv, 2022 - biorxiv.org
Small and isolated wildlife populations face numerous threats to extinction, among which is
the deterioration of fitness due to an accumulation of deleterious genetic variation. Genomic …

The influence of gene flow on population viability in an isolated urban caracal population

CC Kyriazis, LEK Serieys, JM Bishop… - Molecular …, 2024 - Wiley Online Library
Wildlife populations are becoming increasingly fragmented by anthropogenic development.
Small and isolated populations often face an elevated risk of extinction, in part due to …

Preservation of genetic diversity in a highly fragmented population of the gray‐sided vole Myodes rufocanus in an intensive farming region

Y Ishibashi - Ecology and Evolution, 2023 - Wiley Online Library
Individual dispersal plays an important role in preserving genetic diversity in density‐
fluctuating populations of arvicoline rodents. When habitats are fragmented and dispersal …