[HTML][HTML] Non-alcoholic fatty liver disease and diabetes mellitus as growing aetiologies of hepatocellular carcinoma

S Talamantes, M Lisjak, EH Gilglioni… - JHEP Reports, 2023 - Elsevier
Obesity-related complications such as non-alcoholic fatty liver disease (NAFLD) and type 2
diabetes (T2D) are well-established risk factors for the development of hepatocellular …

[HTML][HTML] Peroxisome proliferator-activated receptor gamma and its natural agonists in the treatment of kidney diseases

V Sharma, V Patial - Frontiers in Pharmacology, 2022 - frontiersin.org
Kidney disease is one of the leading non-communicable diseases related to tremendous
health and economic burden globally. Diabetes, hypertension, obesity and cardiovascular …

Ionizing radiation promotes, whereas calorie restriction suppresses, NASH and hepatocellular carcinoma in mice

Y Shang, T Morioka, K Daino… - … Journal of Cancer, 2023 - Wiley Online Library
The pathological conditions of nonalcoholic fatty liver disease and nonalcoholic
steatohepatitis (NASH) are the major risk factors for hepatocellular carcinoma (HCC) …

[HTML][HTML] Coagulation Dysfunctions in Non-Alcoholic Fatty Liver Disease—Oxidative Stress and Inflammation Relevance

MA Robea, IM Balmus, I Girleanu, L Huiban, C Muzica… - Medicina, 2023 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is one of the most common liver diseases. Its
incidence is progressively rising and it is possibly becoming a worldwide epidemic. NAFLD …

[HTML][HTML] Correlation of endoplasmic reticulum stress patterns with the immune microenvironment in hepatocellular carcinoma: a prognostic signature analysis

K Zhan, X Yang, S Li, Y Bai - Frontiers in Immunology, 2023 - frontiersin.org
Backgrounds The extended duration of endoplasmic reticulum stress (ERS) can impact the
progression of hepatocellular carcinoma (HCC) and the efficacy of immunotherapies by …

[HTML][HTML] Human papilloma virus positive oropharyngeal squamous cell carcinoma and the immune system: pathogenesis, immunotherapy and future perspectives

A Khoo, M Boyer, Z Jafri, T Makeham, T Pham… - International Journal of …, 2024 - mdpi.com
Oropharyngeal squamous cell carcinoma (OPSCC), a subset of head and neck squamous
cell carcinoma (HNSCC), involves the palatine tonsils, soft palate, base of tongue, and …

[HTML][HTML] Identification of ZBTB9 as a potential therapeutic target against dysregulation of tumor cells proliferation and a novel biomarker in Liver Hepatocellular …

Z Zhang, L Wu, J Li, J Chen, Q Yu, H Yao, Y Xu… - Journal of Translational …, 2022 - Springer
Background Zinc finger and bric-a-brac/tramtrack/broad (ZBTB) domain-containing proteins
have been reported to be associated with many tumors' development. However, in tumor …

Nuclear receptor imaging in vivo—clinical and research advances

EE Parent, AM Fowler - Journal of the Endocrine Society, 2023 - academic.oup.com
Nuclear receptors are transcription factors that function in normal physiology and play
important roles in diseases such as cancer, inflammation, and diabetes. Noninvasive …

[HTML][HTML] PPARs and the kynurenine pathway in melanoma—Potential biological interactions

K Walczak, A Gerkowicz, D Krasowska - International Journal of …, 2023 - mdpi.com
Peroxisome proliferator-activated receptors (PPARs) are ligand-activated transcription
factors involved in various physiological and pathological processes within the skin. PPARs …

[HTML][HTML] Nano-revolution in hepatocellular carcinoma: A multidisciplinary odyssey-Are we there yet?

HD Lee, LY Yuan - World Journal of Hepatology, 2024 - ncbi.nlm.nih.gov
In this editorial we comment on the review by Zhou et al reviewing the landscape of
nanomedicine in the treatment of hepatocellular carcinoma (HCC). We focus on the …