Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by the
accumulation of inflammatory cells into the synovium and the destruction of joints. Cytokines …

Publisher Summary This chapter summarizes the rationale for anti-tumor necrosis factor-α
(anti-TNFα) antibody therapy and its clinical effects, which have been remarkably …

Abstract Interleukin 15 (IL–15) is a novel cytokine with interleukin–2–like activity. It is also a
potent T–lymphocyte chemoattractant. Rheumatoid arthritis (RA) is a chronic inflammatory …

Onset of rheumatoid arthritis (RA) is widely believed to be preceded by exposure to some
environmental trigger such as bacterial infectious agents. The influence of bacteria on RA …

Objective. To study the production of interleukin‐13 (IL‐13) in rheumatoid synovium and the
effects of recombinant IL‐13 on the phenotype and function of synovial fluid (SF) …

Many of the major human diseases, both infectious (septic shock syndromes) and idiopathic
(for example, rheumatoid arthritis), are driven by the production of the pro‐inflammatory …

Infection with mycobacterial species, including Mycobacterium tuberculosis, has long been
implicated in the etiopathology of rheumatoid arthritis (RA) on the basis of clinical and …

The aim of this thesis study is to determine the relation among measurement, angle and
index values taken from calcaneuses of the individuals and calcaneal spur, and the …

Die Ätiologie der RA ist bis heute nicht entschlüsselt. Es wird vermutet, daß die
autoimmunen Prozesse in entsprechenden Personen mit genetischer Prädispositon durch …

Better understanding of the immunopathogenesis of rheumatoid arthritis over the past few
decades has promoted the innovation of new therapeutic approaches targeting the disease …