Hypoxia a hallmark of solid tumors makes hypoxic cells radioresistant. On the other
hand, DNA, the main target of anticancer therapy, is not sensitive to the near UV photons …

DNA damage by endogenous and exogenous agents is a serious concern, as the damaged
products can affect genome integrity severely. Damage to DNA may arise from various …

Enediynes undergo a Bergman cyclization reaction to form the labile 1, 4‐didehy‐
drobenzene (p‐benzyne) biradical. The energetics of this reaction and the related Schreiner …

All practically possible hydrogen abstraction reactions for guanosine and uridine have been
investigated through quantum chemical calculations of energy barriers and rate constants …

The accessibility of all possible reaction paths for the reaction between the nucleobase
adenine and the• OH radical is investigated through quantum chemical calculations of …

Solvation can alter reaction mechanisms through hydrogen bonding, ion–dipole
interactions, and van der Waals forces to mention a few. In the study of radiation damage to …

It is well known that water plays an important part in almost all biological systems and that
inclusion of solvation effects might therefore be of utmost importance in studies of radiation …

Publication – Consequences of electron attachment to modified nucleosides incorporated
into DNA – University of Gdańsk Skip to main menu Skip to main content Knowledge base …

The hydrogen abstraction and addition reactions of OH radical with A· U base pair have
been explored by using density functional theory (DFT) both in gas phase and in aqueous …

The reaction mechanism and kinetics for the abstraction of hydrogen and addition of
hydroxyl radical (OH) to 2′-deoxycytidine have been studied using density functional …