Depression is one of the most debilitating psychiatric disorders affecting people of all ages
worldwide. Despite significant heterogeneity between studies, increased inflammation and …

Depression is currently treated by pharmacotherapies that can elicit debilitating side effects
for patients. Novel treatment options with limited side effects are currently being researched …

Social stress is a risk factor for psychiatric disorders, however only a subset of the population
is susceptible while others remain resilient. Inflammation has been linked to the …

A large body of evidence has emerged linking stressful experiences, particularly from one's
social environment, with psychiatric disorders. However, vast individual differences emerge …

Background Neuronal dysfunction caused by neuroinflammation triggered by the stimulation
of matrix metalloproteinases and the subsequent release of pro-inflammatory cytokines, as a …

Major depression is a public health problem, affecting 121 million people worldwide.
Patients suffering from depression present high rates of morbidity, causing profound …

Background Cisplatin is considered one of the most effective and commonly used
chemotherapeutic drugs, but despite its high therapeutic effectiveness, most patients treated …

Idiosyncratic drug induced liver injury (DILI) is one of the most serious hazards that could be
induced due to the misuse of drugs. Diclofenac has long been well-known to prompt such …

Resveratrol (RSV) is a natural polyphenol with diverse biological activities, including potent
hepato-protective and antidepressant-like effects. Fluoxetine (FLX) is one of the most …

A simple, efficient and reliable analytical method was developed and used for the
determination of the fluvoxamine drug (FLV) in pharmaceutical preparations and biological …