Droplet-based microfluidics in biomedical applications
Droplet-based microfluidic systems have been employed to manipulate discrete fluid
volumes with immiscible phases. Creating the fluid droplets at microscale has led to a …
volumes with immiscible phases. Creating the fluid droplets at microscale has led to a …
Droplet microfluidics—A tool for single‐cell analysis
HN Joensson… - Angewandte Chemie …, 2012 - Wiley Online Library
Droplet microfluidics allows the isolation of single cells and reagents in monodisperse
picoliter liquid capsules and manipulations at a throughput of thousands of droplets per …
picoliter liquid capsules and manipulations at a throughput of thousands of droplets per …
Microdroplets in microfluidics: an evolving platform for discoveries in chemistry and biology
AB Theberge, F Courtois, Y Schaerli… - Angewandte Chemie …, 2010 - Wiley Online Library
Microdroplets in microfluidics offer a great number of opportunities in chemical and
biological research. They provide a compartment in which species or reactions can be …
biological research. They provide a compartment in which species or reactions can be …
Rapid detection of single bacteria in unprocessed blood using Integrated Comprehensive Droplet Digital Detection
Blood stream infection or sepsis is a major health problem worldwide, with extremely high
mortality, which is partly due to the inability to rapidly detect and identify bacteria in the early …
mortality, which is partly due to the inability to rapidly detect and identify bacteria in the early …
Analytical detection techniques for droplet microfluidics—A review
Y Zhu, Q Fang - Analytica chimica acta, 2013 - Elsevier
In the last decade, droplet-based microfluidics has undergone rapid progress in the fields of
single-cell analysis, digital PCR, protein crystallization and high throughput screening. It has …
single-cell analysis, digital PCR, protein crystallization and high throughput screening. It has …
Integrated microreactors for reaction automation: new approaches to reaction development
JP McMullen, KF Jensen - Annual review of analytical chemistry, 2010 - annualreviews.org
Applications of microsystems (microreactors) in continuous-flow chemistry have expanded
rapidly over the past two decades, with numerous reports of higher conversions and yields …
rapidly over the past two decades, with numerous reports of higher conversions and yields …
Analytical tools integrated in continuous-flow reactors: which one for what?
M Rodriguez-Zubiri, FX Felpin - Organic Process Research & …, 2022 - ACS Publications
The concept and practices of chemical synthesis are being profoundly transformed toward
the development of fully autonomous continuous processes. Critical to the development of …
the development of fully autonomous continuous processes. Critical to the development of …
SERS-based detection of biomolecules
D Cialla, S Pollok, C Steinbrücker, K Weber, J Popp - Nanophotonics, 2014 - degruyter.com
In order to detect biomolecules, different approaches using for instance biological,
spectroscopic or imaging techniques are established. Due to the broad variety of these …
spectroscopic or imaging techniques are established. Due to the broad variety of these …
The potential of microfluidic water-in-oil droplets in experimental biology
Y Schaerli, F Hollfelder - Molecular Biosystems, 2009 - pubs.rsc.org
The comprehensive characterisation of complex parameter space in '-omics' technologies
requires high-throughput systems. In vitro compartmentalisation of reactions in water-in-oil …
requires high-throughput systems. In vitro compartmentalisation of reactions in water-in-oil …
Highly reproducible immunoassay of cancer markers on a gold-patterned microarray chip using surface-enhanced Raman scattering imaging
This paper reports a highly reproducible immunoassay of cancer markers using surface-
enhanced Raman scattering (SERS) imaging. SERS is a highly sensitive detection method …
enhanced Raman scattering (SERS) imaging. SERS is a highly sensitive detection method …