Molecular Regulator Driving Endometriosis Towards Endometrial Cancer: A Multi-Scale Computational Investigation to Repurpose Anti-Cancer drugs
S Mahema, J Roshni, J Raman, SF Ahmad… - Cell Biochemistry and …, 2024 - Springer
Endometriosis is a gynecological disorder among reproductive-aged women. Recent
epidemiological investigations suggest endometriosis increases the risk of endometrial …
epidemiological investigations suggest endometriosis increases the risk of endometrial …
A concise review on miRNAs as regulators of colon cancer stem cells and associated signalling pathways
A Banerjee, D Deka, M Muralikumar… - Clinical and …, 2023 - Springer
Despite recent therapy advances and a better understanding of colon cancer biology, it
remains one of the major causes of death. The cancer stem cells, associated with the …
remains one of the major causes of death. The cancer stem cells, associated with the …
In-silico identification of small molecule benzofuran-1, 2, 3-triazole hybrids as potential inhibitors targeting EGFR in lung cancer via ligand-based pharmacophore …
Lung cancer is one of the most common and deadly types of cancer worldwide, and the
epidermal growth factor receptor (EGFR) has emerged as a promising therapeutic target for …
epidermal growth factor receptor (EGFR) has emerged as a promising therapeutic target for …
Natural compound targeting BDNF V66M variant: insights from in silico docking and molecular analysis
Abstract Brain-Derived Neurotrophic Factor (BDNF) is a neurotrophin gene family gene that
encodes proteins vital for the growth, maintenance, and survival of neurons in the nervous …
encodes proteins vital for the growth, maintenance, and survival of neurons in the nervous …
In-silico design, pharmacophore-based screening, and molecular docking studies reveal that benzimidazole-1,2,3-triazole hybrids as novel EGFR inhibitors targeting …
Lung cancer is a complex and heterogeneous disease, which has been associated with
various molecular alterations, including the overexpression and mutations of the epidermal …
various molecular alterations, including the overexpression and mutations of the epidermal …
Identification and exploration of quinazoline-1, 2, 3-triazole inhibitors targeting EGFR in lung cancer
Epidermal growth factor receptor (EGFR) enhances lung cancer development, due to their
inability to permeate the cell membrane, secreted growth factors work through specialized …
inability to permeate the cell membrane, secreted growth factors work through specialized …
[HTML][HTML] Explication of pharmacological proficiency of phytoconstituents from Adansonia digitata Bark: An in vitro and in silico approaches
Compared to other drug discovery sources, traditional medicine has significantly contributed
to developing innovative therapeutic molecules for preventive and curative medicine. The …
to developing innovative therapeutic molecules for preventive and curative medicine. The …
Eleven Crucial Pesticides Appear to Regulate Key Genes That Link MPTP Mechanism to Cause Parkinson's Disease through the Selective Degeneration of …
Pesticides kill neurons, but the mechanism leading to selective dopaminergic loss in
Parkinson's disease (PD) is unknown. Understanding the pesticide's effect on dopaminergic …
Parkinson's disease (PD) is unknown. Understanding the pesticide's effect on dopaminergic …
Drug repositioning to discover novel ornithine decarboxylase inhibitors against visceral leishmaniasis
Visceral leishmaniasis (VL) is caused by Leishmania donovani (Ld), and most cases occur
in Brazil, East Africa, and India. The treatment for VL is limited and has many adverse effects …
in Brazil, East Africa, and India. The treatment for VL is limited and has many adverse effects …
In-silico identification and exploration of small molecule coumarin-1, 2, 3-triazole hybrids as potential EGFR inhibitors for targeting lung cancer
Globally, lung cancer is a significant public health concern due to its role as the leading
cause of cancer-related mortalities. The promising target of EGFR for lung cancer treatment …
cause of cancer-related mortalities. The promising target of EGFR for lung cancer treatment …