Joint modeling under competing risks: Application to survival prediction in patients admitted in Intensive Care Unit for sepsis with daily Sequential Organ Failure …

A Lavalley‐Morelle, JF Timsit, F Mentré… - CPT …, 2022 - Wiley Online Library
Joint models of longitudinal process and time‐to‐event data have recently gained attention,
notably to provide individualized dynamic predictions. In the presence of competing risks …

Joint modeling of monocyte HLA‐DR expression trajectories predicts 28‐day mortality in severe SARS‐CoV‐2 patients

G Baudemont, C Tardivon, G Monneret… - CPT …, 2024 - Wiley Online Library
The recent SarsCov2 pandemic has disrupted healthcare system notably impacting
intensive care units (ICU). In severe cases, the immune system is dysregulated, associating …

Longitudinal and time‐to‐event modeling for prognostic implications of radical surgery in retroperitoneal sarcoma

Y Yao, Z Wang, L Yong, Q Yao, X Tian… - CPT …, 2022 - Wiley Online Library
Retroperitoneal sarcoma (RPS) is a rare malignancy which can be difficult to manage due to
the variety of clinical behaviors. In this study, we aimed to develop a parametric modeling …

Predicting progression‐free survival from measurable residual disease in chronic lymphocytic leukemia

FA Tettamanti, H Kimko, S Sharma… - Clinical and …, 2024 - Wiley Online Library
Association between measurable residual disease (MRD) and survival outcomes in chronic
lymphocytic leukemia (CLL) has often been reported. However, limited quantitative analyses …

Bayesian Joint Model with Latent Time Shifts for Multivariate Longitudinal Data with Informative Dropout

X Wang, MG Larson, Y Tripodis, MP LaValley, C Liu - medRxiv, 2024 - medrxiv.org
Dementia often has an insidious onset with considerable individual differences in disease
manifestation. Nonlinear mixed-effects models with latent time shifts have been proposed to …

Model‐based prediction of progression‐free survival for combination therapies in oncology

M Baaz, T Cardilin, M Jirstrand - CPT: Pharmacometrics & …, 2023 - Wiley Online Library
Progression‐free survival (PFS) is an important clinical metric for comparing and evaluating
similar treatments for the same disease within oncology. After the completion of a clinical …