Successful muscle regeneration relies on the interplay of multiple cell populations. However,
the signals required for this coordinated intercellular crosstalk remain largely unknown …

Myopathic processes affect skeletal muscle and heart. In the muscular dystrophies, which
are a subset of myopathies, muscle cells are gradually replaced by fibrosis and fat, impairing …

Background The dystrophin-glycoprotein complex (DGC) is a critical adhesion complex of
the muscle cell membrane, providing a mechanical link between the extracellular matrix …

Extracellular matrix (ECM) pathologic remodeling underlies many disorders, including
muscular dystrophy. Tissue decellularization removes cellular components while leaving …

Skeletal muscle is a force-producing organ composed of muscle tissues, connective tissues,
blood vessels, and nerves, all working in synergy to enable movement and provide support …

In recent times, the concept of biomimetics has gained widespread acceptance across
different industries. This interdisciplinary field combines principles from biology …

To assess cellular behavior within heterogeneous tissues, such as bone, skin, and nerves,
scaffolds with biophysical gradients are required to adequately replicate the in vivo …

The role of the cellular microenvironment has recently gained attention in the context of
muscle health, adaption, and disease. Emerging evidence supports major roles for the …

Pathological remodeling of the extracellular matrix (ECM) underlies many fibrotic disorders,
including muscular dystrophy. In fibrotic disorders, large matricellular proteins like …

Protein-based monomers are among the most alluring options for achieving improved
results with cutting-edge biomaterials since recent advances in bioartificial and microbiology …