Heavy metals such as Fe, Mn, Cu, Ni, Co, Cd, Zn, Hg and arsenic are for long being
accumulated in soils through industrial waste and sewage disposal. Although some of these …

The formation and accumulation of methylglyoxal (MGO), a highly reactive dicarbonyl
compound, has been implicated in the pathogenesis of type 2 diabetes, vascular …

Heavy metal (HM) toxicity is one of the major abiotic stresses leading to hazardous effects in
plants. A common consequence of HM toxicity is the excessive accumulation of reactive …

Hypertension is a leading risk factor for disease burden worldwide. The kidneys, which have
a high specific metabolic rate, play an essential role in the long-term regulation of arterial …

The formation and accumulation of advanced glycation endproducts (AGEs) are related to
diabetes and other age-related diseases. Methylglyoxal (MGO), a highly reactive dicarbonyl …

The epidemics of insulin resistance (IR) and type 2 diabetes (T2D) affect the first world as
well as less-developed countries, and now affect children as well. Persistently elevated …

The glyoxalase system is a ubiquitous enzymatic network which plays important roles in
biological life. It consists of glyoxalase 1 (GLO1), glyoxalase 2 (GLO2), and reduced …

The objective was to study oxidative status, antioxidant activities, and reactive oxygen
species byproducts in whole blood and mononuclear peripherals cells and their relationship …

Diabetes was the first disease state where evidence emerged for increased formation of
methylglyoxal. Metabolism of methylglyoxal by the glyoxalase system has been linked to the …

Imbalance between production and scavenging of superoxide anion results in hypertension
by the inactivation of nitric oxide, and the increased oxidative stress from the resultant …