A wide array of molecular pathways has been investigated during the past decade in order
to understand the mechanisms by which the practice of physical exercise promotes …

Physical activity is one of the modifiable factors of cognitive decline and dementia with the
strongest evidence. Although many influential reviews have illustrated the neurobiological …

A significant body of work has investigated the effects of acute exercise, defined as a single
bout of physical activity, on mood and cognitive functions in humans. Several excellent …

Physical activity plays an essential role in maintaining a healthy body, yet it also provides
unique benefits for the vascular and cellular systems that sustain a healthy brain. While the …

For the last 4 decades, the question of how to manipulate the serotonergic system with drugs
has been an important area of research in biological psychiatry, and this research has led to …

Data Sources: The databases CINAHL, Embase, Cochrane Database of Systematic reviews,
Cochrane Controlled Trials Register, MEDLINE, and PsycINFO were searched (1806–2008) …

The ingestion of large neutral amino acids (LNAA), notably tryptophan, tyrosine and the
branched-chain amino acids (BCAA), modifies tryptophan and tyrosine uptake into brain and …

Social isolation can exacerbate the negative consequences of stress and increase the risk of
developing psychopathology. However, the influence of living alone on experiences …

The formation of new neurons in the adult central nervous system (CNS) has been
recognized as one of the major findings in neuroanatomical research. The hippocampal …

Voluntary wheel running has long been known to induce precursor cell proliferation in adult
hippocampal neurogenesis in rodents. However, mechanisms that couple activity with the …