A systematic review of the valproic-acid-induced rodent model of autism

D Chaliha, M Albrecht, M Vaccarezza… - Developmental …, 2020 - karger.com
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterised by
repetitive behaviours, cognitive rigidity/inflexibility, and social-affective impairment …

Association between social skills and motor skills in individuals with autism spectrum disorder: a systematic review

R Ohara, Y Kanejima, M Kitamura… - European Journal of …, 2019 - mdpi.com
Social communication and motor skill deficits are prevalent characteristics of individuals with
autism spectrum disorder (ASD). This systematic research review investigates whether and …

Sex-dependent behavioral deficits and neuropathology in a maternal immune activation model of autism

O Haida, T Al Sagheer, A Balbous… - Translational …, 2019 - nature.com
Infections during gestation and the consequent maternal immune activation (MIA) increase
the risk of developing neuropsychiatric disorders in infants and throughout life, including …

Cerebellar and striatal implications in autism spectrum disorders: from clinical observations to animal models

M Thabault, V Turpin, A Maisterrena, M Jaber… - International Journal of …, 2022 - mdpi.com
Autism spectrum disorders (ASD) are complex conditions that stem from a combination of
genetic, epigenetic and environmental influences during early pre-and postnatal childhood …

Repetitive restricted behaviors in autism spectrum disorder: From mechanism to development of therapeutics

J Tian, X Gao, L Yang - Frontiers in neuroscience, 2022 - frontiersin.org
Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder characterized
by deficits in social communication, social interaction, and repetitive restricted behaviors …

Endophenotype trait domains for advancing gene discovery in autism spectrum disorder

MW Mosconi, CJ Stevens, KE Unruh, R Shafer… - Journal of …, 2023 - Springer
Autism spectrum disorder (ASD) is associated with a diverse range of etiological processes,
including both genetic and non-genetic causes. For a plurality of individuals with ASD, it is …

Major motor and gait deficits with sexual dimorphism in a Shank3 mutant mouse model

E Matas, A Maisterrena, M Thabault, E Balado… - Molecular Autism, 2021 - Springer
Background Contrasting findings were reported in several animal models with a Shank3
mutation used to induce various autism spectrum disorder (ASD) symptoms. Here, we aimed …

[HTML][HTML] Three decades of valproate: a current model for studying autism Spectrum disorder

D Zarate-Lopez, AL Torres-Chávez… - Current …, 2023 - ncbi.nlm.nih.gov
Abstract Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder with increased
prevalence and incidence in recent decades. Its etiology remains largely unclear, but it …

Photobiomodulation attenuated cognitive dysfunction and Neuroinflammation in a prenatal Valproic acid-induced autism Spectrum disorder mouse model

UJ Kim, N Hong, JC Ahn - International Journal of Molecular Sciences, 2022 - mdpi.com
Autism spectrum disorder (ASD) is a neurodevelopmental condition characterized by social
communication and interaction disorders, as well as repetitive and restrictive behaviors. To …

Validation of prenatal versus postnatal valproic acid rat models of autism: A behavioral and neurobiological study

EM Elnahas, SA Abuelezz, MI Mohamad… - Progress in Neuro …, 2021 - Elsevier
Despite the increasing prevalence of autism spectrum disorder (ASD), there is still a
deficiency in understanding its exact pathophysiology and treatment, therefore validation of …